ENHANCE
Healthspan & Longevity Support*
- Promotes Longevity, Cellular Renewal & Autophagy
- Supports Heart Health & Mitochondrial Free Radicals
- Assists Cellular Detox & Optimizes Nrf2 Pathways
- Supports Stamina + Endurance & Protein Synthesis
- Maintains Lipid & Blood Sugar Regulation + Energy Production
Active Ingredients: Arginine Alpha-Ketoglutarate, Trimethylglycine, Bergamot Orange Extract, Bergamonte®, Epigallocatechin Gallate, Taxifolin, Spermidine
Other Ingredients: Vegetable Capsule (Hypromellose, Titanium Dioxide)
HOW
Take 3 capsules daily with water or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
3 Capsules
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Benefits
- Promotes Longevity, Cellular Renewal & Autophagy
- Supports Heart Health & Mitochondrial Free Radicals
- Assists Cellular Detox & Optimizes Nrf2 Pathways
- Supports Stamina + Endurance & Protein Synthesis
- Maintains Lipid & Blood Sugar Regulation + Energy Production
-
Ingredients
Active Ingredients: Arginine Alpha-Ketoglutarate, Trimethylglycine, Bergamot Orange Extract, Bergamonte®, Epigallocatechin Gallate, Taxifolin, Spermidine
Other Ingredients: Vegetable Capsule (Hypromellose, Titanium Dioxide)
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How To Use
HOW
Take 3 capsules daily with water or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
3 Capsules
ENHANCE
Formulation
Alpha-Ketoglutarate
- Found In
- Citrus Fruits, Berries, Tomatoes, Spinach (in small amounts)
- Source
- Arginine Alpha-Ketoglutarate
- Benefits
- Blood Pressure, Energy Production
- Science
- 337 published articles
Citrus Bergamot
- Found In
- Bergamot Fruit (Citrus bergamia)
- Source
- Bergamonte®
- Benefits
- Cholesterol, Immune System, Mood, Mental Alertness
- Science
- 471 published articles
Trimethylglycine
- Found In
- Wheat, Beets, Quinoa, Seafood
- Source
- Betaine Anhydrous
- Benefits
- Immune Function, Liver Health, Athletic Performance
- Science
- 9,341 published articles
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Epigallocatechin Gallate
- Found In
- Green Tea
- Source
- Camellia sinensis
- Benefits
- Antioxidant, Mood, Calming Support, Memory
- Science
- 7,138 published articles
Taxifolin
- Found In
- Onions, Milk Thistle, French Maritime Pine Bark
- Source
- Dihydroquercetin
- Benefits
- Liver Health, Detoxification, Brain Health, Immune Function
- Science
- 1,083 published articles
Spermidine
- Found In
- Wheatgerm, Soya beans, Mushrooms, Mature Cheeses
- Source
- Combination of 14-Butanediamine and SAMe
- Benefits
- Energy, Heart, Brain Health
- Science
- 14,420 published articles
Healthspan & Longevity Support*
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OVERVIEW
Enhance is a cutting-edge dietary supplement formulated to support longevity and promote healthy aging. As we age, our cells undergo transformations that impact our well-being and lifespan, including diminished mitochondrial function, reduced autophagy, and decreased cellular renewal. Enhance leverages a precise blend of six key ingredients, including Arginine Alpha-Ketoglutarate (AAKG), Trimethylglycine (TMG), Bergamot Orange Extract, Epigallocatechin Gallate (EGCG), Taxifolin, and Spermidine. These ingredients have demonstrated efficacy in promoting healthspan, optimizing epigenetic aging, and supporting mitochondrial function and autophagy, thus facilitating cellular renewal. By targeting crucial aspects of cellular function such as mitochondrial health, oxidative stress, gene expression, and cellular renewal, Enhance offers a comprehensive approach to support healthy aging and optimize overall cellular well-being, contributing to graceful aging and enhanced longevity.
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INGREDIENTS
Arginine Alpha-Ketoglutarate
Arginine Alpha-Ketoglutarate (AAKG) is a vital molecule in the tricarboxylic acid (TCA) cycle, a central pathway for energy production in cells, and is critical in cellular energy metabolism and functions such as DNA and protein synthesis. AAKG acts as a precursor to nitric oxide (NO), a signaling molecule involved in various cellular processes. By supporting nitric oxide production, AAKG promotes blood flow and oxygen delivery to tissues, optimizing mitochondrial function. Furthermore, AAKG exhibits potent antioxidant properties, reducing oxidative stress and preserving mitochondrial integrity. The combined effects of AAKG on nitric oxide production, blood flow, oxygen delivery, and antioxidation contribute to its ability to promote longevity.1,2
Trimethylglycine
Trimethylglycine (TMG), also known as betaine anhydrous, is a naturally occurring compound with diverse physiological functions. TMG acts as a methyl donor, supporting DNA and histone methylation, which play critical roles in gene expression regulation and maintaining cellular function. By modulating gene expression, TMG helps optimize cellular function and contributes to its longevity-promoting effects.3,4
Bergamote®
Natural polyphenols found in fruits, vegetables, and tea exhibit antioxidant activity, modulation of cell signaling pathways, DNA methylation, and apoptosis. Bergamote® (bergamot orange extract), rich in polyphenols such as flavonoids and citrus bergamia polyphenols (CBPs), offers multiple mechanisms of action that promote longevity. Its potent antioxidant properties neutralize reactive oxygen species (ROS). It has been shown to support cardiovascular health and support healthy cholesterol, blood sugar levels and weight management.5,6,7 Additionally, bergamot orange extract supports endothelial function, promoting blood flow and cardiovascular health.8,9
Epigallocatechin Gallate
Epigallocatechin gallate (EGCG), a polyphenol found in green tea, promotes longevity through various mechanisms. EGCG scavenges free radicals and protects cellular components as a potent antioxidant. Furthermore, EGCG supports autophagy, a cellular process that clears damaged proteins and organelles, promotes cellular function and support longevity.10,11
Taxifolin
Taxifolin, also known as dihydroquercetin, is a flavonoid found in various plant sources that exhibits diverse mechanisms of action contributing to its longevity-promoting effects. It acts as a potent antioxidant, effectively scavenging free radicals and limiting oxidative stress, which can lead to cellular damage and aging. Additionally, taxifolin supports mitochondrial biogenesis and promotes electron transport chain activity, resulting in energy production and cellular respiration.12,13
Spermidine
Spermidine is a polyamine naturally present in various foods and cells. It plays a crucial role in cellular processes such as autophagy and gene expression regulation. Spermidine promotes autophagy, which removes damaged cellular components and supports cellular rejuvenation. By supporting autophagy, spermidine helps maintain cellular health. It also exhibits antioxidant properties, protecting cells from oxidative damage. Furthermore, spermidine optimizes gene expression by interacting with chromatin and influencing histone modifications, contributing to cellular homeostasis and longevity.14,15 -
REFERENCES
1. Allerton TD, Proctor DN, Stephens JM, Dugas TR, Spielmann G, Irving BA. Nutrients. 2018 Jul 19;10(7):921. doi: 10.3390/nu10070921. PMID: 30029482; PMCID: PMC6073798. https://doi.org/10.3390/nu10070921
2. Boccardi V , Paolisso G, Mecocci P . Aging (Albany NY). 2016 Jan;8(1):12-5. doi: 10.18632/aging.100886. https://doi.org/10.18632/aging.100886
3. Shay J, Elbaz HA, Lee I, Zielske SP , Malek MH, Hüttemann M. Oxid Med Cell Longev. 2015;2015:181260. doi: 10.1155/2015/181260. https://doi.org/10.1155%2F2015%2F181260
4. Y ao HT, Li CC, Chang CH. E Nutrients. 2019 Aug 10;11(8):1862. doi: 10.3390/nu11081862. https://doi.org/10.3390/nu11081862
5. Ross Walker, Elzbieta Janda and Vincenzo Mollace. Cardiac Health and Polyphenols. Chp 84, Pg 1085-1103, 2014. http://dx.doi.org/10.1016/B978-0-12-398456-2.00084-0
6. Micaela Gliozzi, Ross Walker, Elzbjeta Janda, Vincenzo Mollace. International Journal of Cardiology Dec 2013, 170(2):140-5. https://doi.org/10.1016/j.ijcard.2013.08.125
7. Vincenzo Mollace, Iolanda Sacco, Elzbieta Janda, Claudio Malara, Domenica V entrice, Carmen Colica, V aleria Visalli, Saverio Muscoli. Fitoterapia 82 (2011) 309–316. https://doi.org/10.1016/j.fitote.2010.10.014
8. Liu P , Huang J, Mei W, Zeng X, Wang C, Wen C, Xu J. Bioengineered. 2021 Dec;12(2):9496-9506. doi: 10.1080/21655979.2021.1996018. https://doi.org/10.1080%2F21655979.2021.1996018
9. Saini RK, Ranjit A, Sharma K, Prasad P , Shang X, Gowda KGM, Keum YS. Antioxidants (Basel). 2022 Jan 26;11(2):239. doi: 10.3390/antiox11020239. https://doi.org/10.3390%2Fantiox11020239
10. Inoue, T., Saito, S., Tanaka, M., Y amakage, H., Kusakabe, T., Shimatsu, A., Ihara, M., & Satoh-Asahara, N. (2019). Proceedings of the National Academy of Sciences, 116(20), 10031–10038. https://doi.org/10.1073/pnas.1901659116
11. Chirumbolo S. Inflamm Allergy Drug Targets. 2010 Sep;9(4):263-85. https://doi.org/10.2174/187152810793358741
12. Emile Andriambeloson and others, The Journal of Nutrition, V olume 128, Issue 12, December 1998, Pages 2324–2333, https://doi.org/10.1093/jn/128.12.2324
13. Li J, Sun M, Cui X, Li C. Int J Mol Sci. 2022 Sep 2;23(17):10020. https://doi.org/10.3390%2Fijms231710020
14. Madeo F, Zimmermann A, Maiuri MC, Kroemer G. J Clin Invest. 2015 Jan;125(1):85-93. https://doi.org/10.1172%2FJCI73946
15. Eisenberg, T., Knauer, H., Schauer, A. et al. Nat Cell Biol 11, 1305–1314 (2009). https://doi.org/10.1038/ncb1975
| Ingredients | Amount Per Serving |
| Arginine Alpha-Ketoglutarate | 500 mg |
| Trimethylglycine (TMG) (as Betaine Anhydrous) | 500 mg |
| Bergamont Orange Extract (citrus bergamia) (Fruit) (Bergamonte®) (38% Bergamot Polyphenolic Fraction® comprised of Neohesperidin, Naringin, Neoeriocitrin, Brutierifin and Melitidin) | 250 mg |
| Epigallocatechin Gallate (EGCG) (from Green Tea 98% Extract) | 100 mg |
| Taxifolin (from Dihydroquercetin) | 10 mg |
| Spermidine | 10 mg |
Other Ingredients: Rice Flour, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose)
Professional Information
People Requiring:
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Anti-Aging Protocols
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High Levels of Physical Activity
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Mitochondrial Support
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Cardiovascular Support
Practitioners Recommend
Enhance: Supplement for Healthy Aging: FAQs
Have more questions? We have answers
InfiniCare—your personal concierge for longevity. Our team of experts, including our on-staff physician, are standing by to ensure world-class service.
Call Us 1-888-819-4640
Our team is located in Dallas, TX, USA
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What is InfiniWell Enhance?
Enhance by InfiniWell is part of the InfiniWell longevity supplement collection. It was developed to support cellular function, antioxidant activity, and general wellness as the body changes over time.The formula combines ingredients that have been explored in scientific research related to cellular energy and metabolic processes. These areas are commonly associated with overall vitality and everyday wellness in adults. -
What are the benefits of Enhance?
Enhance is formulated to support natural cellular processes that contribute to long-term wellness and vitality.Key areas of support include:- Healthy aging: Support normal cellular activity and help the body maintain resilience as it ages
- Mitochondrial function: Support cellular energy production and help maintain metabolic balance
- Cardiovascular wellness: Support normal blood vessel function and healthy lipid metabolism
- Daily vitality: Nutritional support that helps maintain normal energy metabolism for everyday activity and an active lifestyle
- Metabolic balance: Support normal blood glucose and lipid metabolism as part of overall wellness
- Muscle maintenance: Support normal protein metabolism and help maintain muscle tissue as adults age
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What are the ingredients in Enhance?
Each three-capsule serving of Enhance contains a targeted blend of nutrients selected to support cellular wellness and metabolic balance.- Arginine alpha-ketoglutarate: Supports nitric oxide production and amino acid metabolism, which are involved in circulation and cellular energy processes
- Trimethylglycine (betaine): Supports methylation, a biochemical process involved in cellular metabolism and energy production
- Bergamot orange extract (Bergamonte®): A plant extract studied for its role in supporting normal lipid metabolism and metabolic balance
- Epigallocatechin gallate (EGCG): A green tea compound studied for its antioxidant properties and its role in supporting cellular defense against everyday oxidative stress
- Taxifolin: A plant-derived flavonoid that supports antioxidant activity and general cellular wellness
- Spermidine: A naturally occurring compound being studied for its relationship with cellular maintenance processes such as autophagy
- Other ingredients: Vegetable capsule (hypromellose, titanium dioxide)
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What makes Enhance a comprehensive longevity supplement?
Enhance is designed to support several biological processes associated with long-term wellness rather than focusing on just one area.These include:
- Autophagy: Supports the body’s natural cellular recycling process that helps maintain normal cellular function
- Mitochondrial activity: Supports energy production at the cellular level
- Antioxidant pathways: Help the body maintain antioxidant balance in response to everyday environmental stressors
- Energy metabolism: Supports metabolic processes involved in cellular energy and physical activity
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How does Enhance support daily energy and vitality?
Enhance contains amino acid derivatives and plant polyphenols that support cellular energy metabolism. These nutrients support mitochondrial activity, which plays a role in how cells generate energy.Arginine alpha-ketoglutarate supports nitric oxide pathways related to circulation, while trimethylglycine contributes to methylation processes involved in cellular metabolism.
Together, these nutrients support everyday energy and stamina. -
What is autophagy?
Autophagy is a natural process in which cells recycle older or damaged components. This cellular housekeeping process helps maintain normal cell function.Enhance contains spermidine, a compound currently being studied for its relationship to autophagy and cellular maintenance. Research in this area is ongoing. -
Can Enhance support metabolic balance?
Enhance contains bergamot extract and trimethylglycine, ingredients studied for their role in supporting normal metabolic processes, including healthy lipid metabolism and glucose balance.Maintaining balanced metabolic processes is an important part of overall wellness. -
Which ingredients support antioxidant activity?
Several ingredients in Enhance contribute to antioxidant balance:- EGCG: A green tea compound that supports antioxidant activity
- Taxifolin: A plant flavonoid associated with antioxidant support
- Spermidine: A compound being studied for its relationship with cellular maintenance
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What is mitochondrial function?
Mitochondria are structures inside cells that generate energy. Because cells rely on this energy to perform everyday functions, mitochondrial activity is closely tied to overall vitality.Enhance contains nutrients that support mitochondrial activity and cellular energy production. -
What is the Nrf2 pathway?
The Nrf2 pathway is a cellular mechanism involved in the body’s antioxidant response. It helps regulate how cells respond to everyday environmental stressors.Compounds such as EGCG and taxifolin are being studied for their relationship to cellular antioxidant pathways, including the Nrf2 pathway. -
How does Enhance support muscle maintenance?
Enhance contains arginine alpha-ketoglutarate, which supports nitric oxide production and amino acid metabolism. These processes contribute to normal protein metabolism and help maintain muscle tissue.This support may be helpful for adults focused on maintaining an active lifestyle. -
How should I take InfiniWell Enhance?
The suggested use is three capsules daily, taken with water.Always follow the serving instructions on the product label or consult a qualified healthcare professional before starting a new supplement. -
Does Enhance contain stimulants?
No. Enhance is a stimulant-free formula and does not contain caffeine or similar ingredients. -
Who is Enhance for?
Enhance may be a good fit for adults who want nutritional support for:- Cellular wellness
- Daily energy and vitality
- Mitochondrial activity
- Cardiovascular wellness
- Healthy aging
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What makes InfiniWell longevity supplements different?
InfiniWell longevity supplements are designed with several principles in mind:- Research-informed formulations: Ingredients selected based on emerging scientific research
- Transparent labeling: Clear ingredient lists with no unnecessary additives
- Targeted formulations: Products designed to support specific aspects of wellness
- Quality manufacturing: Produced in facilities that follow Good Manufacturing Practices (GMP) for consistency and quality
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Are lifestyle habits important for healthy aging?
Yes. Supplements are only one part of a broader wellness strategy. Daily habits commonly associated with long-term wellness include:- Eating a balanced diet rich in whole foods
- Staying physically active
- Getting adequate sleep
- Managing everyday stress
- Protecting skin from excessive sun exposure
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Should you take longevity supplements?
Some adults choose longevity-focused supplements to support cellular processes associated with aging and overall wellness.Ingredients found in these formulas are often studied for their relationship with antioxidant activity, metabolic balance, and cellular maintenance.
Because research in this field continues to develop, results can vary from person to person. Supplements are not intended to replace professional medical care. -
Where to buy Enhance
Enhance can be purchased directly through the InfiniWell website or through authorized retailers.When choosing longevity supplements, many people look for formulas that:
- Contain research-supported ingredients
- Support multiple biological pathways
- Are manufactured to high quality standards
- Provide transparent labeling
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Disclaimer
This content is provided for general informational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any new supplement or making changes to your wellness routine.