DHH-B
Mood Support*
- Promotes an Overall Sense of Calm
- Helps Promote Relaxation & Reduced Nervousness
- Maintains Healthy Neurotransmitter Release (Specifically, GABA)
- Promotes Both Healthy REM & Non-REM Sleep Cycles
Active Ingredient: DHH-B (Dihydrohonokiol-B)
Other Ingredients: Cellulose, Rice Powder, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose, Titanium Dioxide)
HOW
Take 1 capsule as needed or as directed by your healthcare practitioner.
WHEN
As needed
DOSE
1 Capsule
NOTES
SHOULD NOT BE TAKEN WITH ALCOHOL.
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Benefits
- Promotes an Overall Sense of Calm
- Helps Promote Relaxation & Reduced Nervousness
- Maintains Healthy Neurotransmitter Release (Specifically, GABA)
- Promotes Both Healthy REM & Non-REM Sleep Cycles
-
Ingredients
Active Ingredient: DHH-B (Dihydrohonokiol-B)
Other Ingredients: Cellulose, Rice Powder, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose, Titanium Dioxide)
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How To Use
HOW
Take 1 capsule as needed or as directed by your healthcare practitioner.
WHEN
As needed
DOSE
1 Capsule
NOTES
SHOULD NOT BE TAKEN WITH ALCOHOL.
Formulation
DHH-B
- Found In
- Magnolia Extract
- Source
- Dihydrohonokiol-B
- Benefits
- Stress, Sleep, Brain Support
- Science
- 1,186 published articles
Overview
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OVERVIEW
Dihydrohonokiol-B (DHH-B) is a natural compound derived from the root bark of Magnolia officinalis, a traditional Chinese medicinal plant. It has garnered considerable attention in recent years due to its potential therapeutic properties, having 20x the strength of standard magnolia extract. DHH-B promotes a sense of tranquility and calmness. By targeting key neurotransmitters, this remarkable compound helps in the management of stress and supports relaxation. Its unique mechanism of action encourages a balanced state of mind, allowing you to navigate daily challenges with ease. Additionally, DHH-B promotes healthy sleep patterns, allowing individuals who take it to achieve restful nights and wake up feeling refreshed and rejuvenated.
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IMPACT ON GABA AND OTHER NEUROTRANSMITTERS
DHH-B exerts its biological effects through multiple mechanisms, contributing to its diverse cellular activities. One of its primary mechanisms of action is through modulating GABA, one of the most important inhibitory neurotransmitters; DHH-B specifically aids in the functionality of the GABA receptors.
In addition to its GABAergic effects, DHH-B also supports the release and reuptake of various other neurotransmitters, including dopamine, serotonin, and norepinephrine. By promoting levels of these neurotransmitters, DHH-B exhibits potential support for mood, relaxation, and cognitive function. -
ANTIOXIDANT SUPPORT
Another important aspect of DHH-B is its ability to support the healthy levels of production of certain stress related chemicals called cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukins (IL-1β, IL-6).
Furthermore, DHH-B displays robust antioxidant properties. It is a scavenger of reactive oxygen species (ROS) and upregulates endogenous antioxidant enzymes. These antioxidant effects contribute to its neuroprotective and anti-aging properties. DHH-B’s antioxidant and neuroprotective properties make it a candidate for supporting neurologic physiology and functionality to promote both short term and long term brain health.
Furthermore, DHH-B displays robust antioxidant properties. It is a scavenger of reactive oxygen species (ROS) and upregulates endogenous antioxidant enzymes. These antioxidant effects contribute to its anti-aging properties. -
REFERENCES
1. Lin Y , Li Y , Zeng Y , Tian B, Qu X, Y uan Q, Song Y . Front Pharmacol. 2021 Mar 17;12:632767. doi: 10.3389/fphar.2021.632767. PMID: 33815113; PMCID: PMC8010308.
2. Shen JL, Man KM, Huang PH, Chen WC, Chen DC, Cheng YW, Liu PL, Chou MC, Chen YH. Molecules. 2010 Sep 16;15(9):6452-65. doi: 10.3390/molecules15096452. PMID: 20877235; PMCID: PMC6257695.
3. Hou Y , Aboukhatwa MA, Lei DL, Manaye K, Khan I, Luo Y . Neuropharmacology. 2010 May;58(6):911-20. doi: 10.1016/j.neuropharm.2009.11.002. Epub 2009 Nov 14. PMID: 19917299; PMCID: PMC2838959.
4. Woo SM, Seo SU, Kubatka P , Min KJ, Kwon TK. Biomolecules. 2019 Dec 6;9(12):838. doi: 10.3390/biom9120838. PMID: 31817770; PMCID: PMC6995549.
5. Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP . Curr Mol Med. 2012 Dec;12(10):1244-52. doi: 10.2174/156652412803833508. PMID: 22834827; PMCID: PMC3663139.
| Ingredients | Amount Per Serving |
| DHH-B (dihydrohonokiol-B) (derived from magnolia bark) | 7.5 mg |
Other Ingredients: Cellulose, Rice Powder, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose, Titanium Dioxide)
Professional Information
People Requiring:
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Stress & Sleep Protocols
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Mood & Neurological Protocols
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FAQs
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What is InfiniWell's DHH-B supplement?
InfiniWell's DHH-B supplement features dihydrohonokiol-B (DHH-B), a potent compound extracted from the root bark of Magnolia officinalis—an ancient medicinal herb traditionally used for relaxation and stress relief.Research suggests that DHH-B may offer extra nutritional support for individuals dealing with stress, sleep disturbances, or mood fluctuations. Known for its calming effect, DHH-B promotes a natural sense of tranquility and helps the body manage stress more effectively.
Each InfiniWell DHH-B capsule delivers 7.5 mg of this bioactive ingredient, blended with organic herbs carefully chosen to support neurological and emotional well-being. The formula is crafted for maximum absorption and consistent performance. -
What are the benefits of the DHH-B supplement?
When taken consistently, InfiniWell’s DHH-B supplement may offer a wide range of support for emotional, neurological, and cognitive wellness.As a natural compound derived from magnolia bark, it's formulated to promote calm and resilience during stressful moments—without relying on synthetic sedatives. The supplement includes carefully selected herbs and a highly bioavailable form of DHH-B, allowing for maximum absorption and consistent results over time.
Key benefits include:
Stable and positive mood
This DHH-B supplement is formulated to aid mood support by encouraging emotional balance—even during stressful or mentally taxing days. It works by helping promote gamma-aminobutyric acid (GABA) activity and regulate key neurotransmitters like serotonin and dopamine, which are closely tied to mood stabilization and anxiety levels.
By promoting a steady mental state, DHH-B may help reduce occasional mood fluctuations linked to fatigue, overwhelm, or emotional ups and downs.
Healthy neurotransmitter release
DHH-B supports natural levels of mood-regulating neurotransmitters, including GABA, dopamine, and serotonin—key players in emotional clarity, focus, and overall well-being. By optimizing GABA activity, this supplement helps promote a relaxed mental state during stressful moments.
Whether you're navigating everyday pressures or simply aiming for mental clarity, DHH-B helps maintain the chemical balance that supports effective stress management and an overall sense of calm.
Improved sleep quality
DHH-B encourages both healthy REM and non-REM sleep cycles, promoting rest and helping the body achieve deeper, more restorative sleep. By reducing adrenaline levels and calming overactive brain activity, it supports a natural state of relaxation that can make it easier to fall and stay asleep.
Its effects on neurotransmitters and anxiety levels also contribute to better overall sleep hygiene. Many users report waking up feeling more refreshed, focused, and better able to manage their day after consistent use.
Stress support and resilience
DHH-B may help the body respond more effectively to stress by targeting key pathways involved in hormonal and neurological balance. It supports the hypothalamic-pituitary-adrenal (HPA) axis—a central player in managing significant stress-related hormone activity, including cortisol, as well as immune system function.
By quieting excitatory neurons and promoting the release of calming neurotransmitters like GABA, DHH-B contributes to a more balanced mood and greater stress tolerance. Regular use may lower unhealthful cortisol levels and help maintain a steadier stress response throughout the day.
Neurosupportive properties
DHH-B offers many benefits beyond mood and sleep—it also provides neuroprotective support by helping neutralize reactive oxygen species (ROS), which can damage brain cells over time. Its antioxidant properties may help support brain health as you age.
By increasing GABA activity and supporting relaxation, DHH-B contributes to a more resilient nervous system.
Support for cognitive function
DHH-B may assist in maintaining cognitive function by helping regulate GABA and dopamine activity—especially when stress, fatigue, or poor sleep disrupts focus, memory, or mental clarity. These neurotransmitters are closely involved in attention and processing speed, both of which can suffer during periods of prolonged mental strain.
Overall, DHH-B serves as an all-natural supplement designed to help you manage stress, promote restful sleep, and maintain emotional and cognitive balance—even on your most stressful days. -
How does DHH-B work?
DHH-B targets the central nervous system by influencing GABA receptors—key players in reducing excitatory neuron activity. It helps quiet overstimulated brain signals while enhancing the release and reuptake of neurotransmitters like dopamine and serotonin. This dual action promotes a calm state of mind and improved cognitive function.In addition, DHH-B acts as a scavenger of reactive oxygen species, supporting antioxidant defense systems that protect against stress-related cellular damage. -
What makes DHH-B different from regular magnolia bark supplements?
DHH-B is a highly concentrated and refined extract—about 20 times more potent than standard magnolia bark. This allows for targeted support of neurological health, with even smaller amounts delivering meaningful effects.It’s a focused formula for those seeking an effective calm mood supplement without sedatives or synthetic ingredients. -
What is the gut-brain connection in relation to mood and stress?
While DHH-B primarily acts through the central nervous system, its calming effects may also support the gut-brain axis indirectly. By reducing the stress hormone response and modulating neurotransmitters, it may help support overall well-being, including the body’s natural stress and digestive responses. -
Is DHH-B suitable for promoting restful sleep?
Yes. DHH-B encourages healthy sleep patterns by modulating neurotransmitters involved in both relaxation and sleep cycles. Users often report falling asleep more easily and experiencing deeper, more restorative sleep without grogginess. -
Are there any side effects?
InfiniWell’s DHH-B supplement is made from all-natural ingredients and is generally well tolerated. It contains no artificial additives and is formulated to support mood and sleep, with no known common side effects.However, it should not be taken with alcohol, and anyone with medical conditions or on medication should consult their healthcare provider before use. -
How do I take DHH-B?
Take one capsule with water as needed—ideally during times of stress or in the evening to promote restful sleep. The recommended dose is one capsule per use. Do not take DHH-B with alcohol. -
Is this a stimulant?
No. DHH-B works with the body's natural neurotransmitters and does not contain caffeine or synthetic stimulants. Its calming effects come from increasing GABA activity and regulating stress-related hormones like cortisol. -
What’s inside each capsule?
Each serving contains 7.5 mg of DHH-B derived from magnolia bark. Other ingredients include:- Cellulose: A plant-based filler used to provide capsule structure
- Rice powder: A natural flow agent that helps evenly distribute ingredients
- Hydroxypropyl methylcellulose: A plant-derived compound used to stabilize the formula
- Magnesium stearate: A common vegetable-based lubricant that prevents clumping during manufacturing
- Silicon dioxide: An anti-caking agent that keeps the powder free-flowing
- Vegetable capsule (hypromellose, titanium dioxide): A plant-based capsule shell used to encase the ingredients, with titanium dioxide added for opacity
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What are peptides and bioactive compounds for mood and stress?
Bioactive compounds like DHH-B support the nervous system by interacting with key receptors and chemical pathways.In this case, DHH-B mimics some functions of GABA—a neurotransmitter that promotes calm—making it a promising natural compound for mood support and relaxation during times of occasional stress. -
How can I choose the best DHH-B supplement?
Look for these quality indicators:- Clear ingredient listing: DHH-B should be specifically identified and quantified.
- Source transparency: InfiniWell uses a magnolia-derived form known for its purity.
- GMP-compliant manufacturing: InfiniWell adheres to Good Manufacturing Practices for safety and quality.
- No artificial additives: It should be free from preservatives, synthetic colors, or sweeteners.
InfiniWell’s DHH-B supplement delivers powerful, all-natural support for stress, sleep, and emotional balance in a convenient capsule form.
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Terms to know
Glossary:- Cytokines: Proteins involved in immune responses. Elevated levels are often associated with heightened stress and immune system activation.
- DHH-B: A concentrated extract from Magnolia officinalis, shown to support calm and neurological health.
- GABA: Short for gamma-aminobutyric acid, a key neurotransmitter involved in relaxation.
- Hydroxypropyl methylcellulose: A plant-derived capsule material used to maximize absorption of active ingredients by improving stability and delivery.
- Magnolia bark: An ancient medicinal herb used in traditional Chinese medicine for calming effects.
- Neurotransmitters: Chemical messengers like dopamine and serotonin that regulate mood and cognition.
- Reactive oxygen species (ROS): Harmful byproducts of stress and metabolism, targeted by antioxidants.
- REM: Short for rapid eye movement sleep, a key stage of the sleep cycle linked to dreaming, memory consolidation, and emotional processing.