BPC-157 Probiotic | ABC
Peptide | Live Probiotic*
- Supports Healthy Gut Microbiota
- Aids in Optimizing Gut Barrier Integrity
- Helps Promote GLP-1 Production
- Promotes Leaner Body Composition
Active Ingredients: Akkermansia (Live Akkermansia muciniphila), Body Protective Compound 250mcg (as BPC-157 Arginate Salt), Sunfiber® Prebiotic (Galactomannan Fiber), Salcaprozate Sodium (SNAC)
Other Ingredients: Vegetable Capsule (Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
HOW
Take 1-2 capsules two times daily with water or as directed by your healthcare practitioner.
WHEN
Daily
SERVING SIZE
1-2 Capsules
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Benefits
- Supports Healthy Gut Microbiota
- Aids in Optimizing Gut Barrier Integrity
- Helps Promote GLP-1 Production
- Promotes Leaner Body Composition
-
Ingredients
Active Ingredients: Akkermansia (Live Akkermansia muciniphila), Body Protective Compound 250mcg (as BPC-157 Arginate Salt), Sunfiber® Prebiotic (Galactomannan Fiber), Salcaprozate Sodium (SNAC)
Other Ingredients: Vegetable Capsule (Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
-
How To Use
HOW
Take 1-2 capsules two times daily with water or as directed by your healthcare practitioner.
WHEN
Daily
SERVING SIZE
1-2 Capsules
Formulation
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BPC-157
- Found In
- Human Digestive System
- Source
- 15 Amino Acid Sequence with Arginate Salt Carrier
- Benefits
- Muscle, Joint & Gut
- Science
- 195 published articles
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Akkermansia
- Found In
- Human Gut Microbiome
- Source
- Isolated live Akkermansia muciniphilia
- Benefits
- Digestive Support, Promotes GLP-1 Production
- Science
- 1403 Published Articles
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Sunfiber
- Found In
- Human Gut Microbiome
- Source
- Galactomannan/Hydrolyzed Guar Gum
- Benefits
- Gut Barrier Integrity, Digestive Support
- Science
- 196 Published Articles
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SNAC
- Found In
- Synthesized
- Source
- Salcoprozate Sodium
- Benefits
- Oral Peptide Bioavailability
- Science
- 75 published articles
Prebiotic | Live Probiotic | Peptide*
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OVERVIEW
ABC (Akkermansia-BPC-Complex) provides a new approach to cellular longevity via gut health and metabolic optimization. Informed by the latest research on microbiome profiles in Centenarians. This "first-of-it's-kind" formulation is at the cutting edge of longevity science. Two primary areas emerge from the data as being critical for longevity: gut barrier integrity and metabolic function, especially as it relates to GLP-1. ABC is designed specifically to harness the synergistic power of Akkermansia, BPC-157, and Sunfiber® to support metabolic optimization and microbiome profiles found amongst blue zone Centenarians.
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INGREDIENTS
AKKERMANSIA & BPC-157 BASICS
First, it is important to understand the biochemical role Akkermansia muciniphila plays in the gut as it relates to metabolic health. It all comes down to its interactions with glucagon-like peptide-1 (GLP-1), an important hormone produced by the intestinal cells, which plays a vital role in regulating glucose metabolism and insulin secretion. Akkermansia muciniphila is known to facilitate the natural production and secretion of GLP-1 in the intestine by utilizing mucin, a glycoprotein present in the mucus lining of the gut. as its primary source of energy.1 During the process of mucin degradation, Akkermansia releases metabolites that stimulate the intestinal L-cells to secrete more GLP-1.2 The increased levels of GLP-1 then act on various tissues, such as the pancreas, liver, and muscles, to promote glucose metabolism, support insulin sensitivity, and regulate appetite. ultimately contributing to overall metabolic health.3
BPC-157, on the other hand, plays an important supporting role via its effects on gut tissue and barrier integrity. This peptide is responsible for maintaining and continuously supporting the intestinal architecture. which allows the myriad of chemical interactions to occur without interruption within the gut ecosystem.
BPC-157 / AKKERMANSIA SYNERGY
Because the biochemical relationship between Akkermansia and the intestinal barrier is heavily dependent on a high level of structural integrity within the gut lining, BPC-157 serves as the ideal companion. As BPC-157 plays a vital role in rejuvenating and maintaining gut tissues, supporting barrier function, it creates the optimaI environment for Akkermansia's broad biochemical function.
Additionally, Sunfiber serves as a rich prebiotic source for short-chain fatty acid production, in particular butyrate. As a trio, they all work in harmony to support a healthy gut microbiome, improve nutrient absorption and optimize metabolic function. This synergistic interaction lays the foundation for longevity by fostering a resilient gut environment that contributes to overall healthspan and vitality.
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REFERENCES
1. Derrien, M. et al. (2004). Bulletin of the IDF, 388, pp.107-112.
2. Plovier. H. et al. (2017). Nature Medicine, 23(1), pp.107-113.
3. Baothman OA, Zamzami MA, Ta her I, Abu baker J, Abu-Farha M. Lipids Health Dis. 2016 Jun 18;15:108.
4. Rodrigues VF, Elias-Oliveira J, Pereira fs. Pereira JA, Barbosa SC, Machado MSG, Carlos D. Front lmmunol. 2022 Jul 7;13:934695.
5. Depommier C., Everard A., Druart C .. Plovier H .. V an Hui M .. Vieira-Silva S., Falony G .. Raes J., Maiter D., Delzenne N.M .. et al. Nat. Med. 2019;25:1096-1103.
6. Wang z. Cui S, Zhang T, Wang W, Li J, Chen YQ. Zhu SI. mSystems. 2023 Oct 26;8(5):e0057323.
7. Everard A., Belzer C .. Geurts L. Ouwerkerk J.P .. Druart C .. Bindels LB., Guiot Y .. Derrien M .. Muccioli G.G .. Delzenne N.M .. et al. Proc. Natl. Acad. Sci. USA. 2013;110:9066-9071.
8. Deng L. Ou z .. Huang D .. Li C., Luz .. Liu w .. Wu F .. Nong C .. Gao J .. Peng Y . Microb. Pathog. 2020;147:104353.
9. Ai X. Liu Y . Shi J, Xie X, Li L, Duan R. Lv Y , Xiong K. Miao Y , Zhang Y . Appl Microbial Biotechnol. 2024 Apr 15;108(1):300.
| Ingredients | Amount Per Serving |
Akkermansia (Live Akkermansia muciniphila) | 500 Million AFU |
| Body Protective Compound 250mcg (as BPC-157 Arginate Salt) | 250mcg |
| Sunfiber® Prebiotic (Galactomannan Fiber) | 250mg |
| Salcaprozate Sodium (SNAC) | 1.5mg |
Other Ingredients: Vegetable Capsule
(Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
Professional Information
People Requiring:
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Comprehensive Digestive Support
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Metabolic, Specifically GLP-1, Support
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Gut-Brain Axis Maintenance
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Intestinal Permeability Support
Practitioners Recommend:
REPARACIÓN Y RECUPERACIÓN
Muscle, Joint, Gut-Brain Axis & Digestive Support*
BPC-157 Probiotic | ABC FAQs
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What is InfiniWell's BPC-157 Probiotic supplement?
InfiniWell’s BPC-157 Probiotic is a gut health supplement made with Akkermansia muciniphila, BPC-157 (as arginate salt), Sunfiber prebiotic, and salcaprozate sodium (SNAC).- Akkermansia muciniphila: A beneficial gut bacterium that helps maintain the gut lining and supports a balanced gut environment.
- BPC-157 (as arginate salt): A peptide that may support the stomach and intestinal lining and help keep digestive function on track.
- Sunfiber (partially hydrolyzed guar gum): A gentle prebiotic fiber that feeds good gut bacteria and supports regular digestion without causing gas or bloating.
- SNAC: An ingredient that helps the body absorb BPC-157 more effectively, so it can work where it’s needed in the digestive tract.
This combination is designed to support gut microbiota composition, gut barrier integrity, and natural metabolic processes.
Each BPC-157 Probiotic serving provides clinically relevant ingredients in an oral format intended to enhance absorption. Take 1–2 capsules twice daily with water or as directed by your healthcare provider. -
What are the benefits of BPC-157 Probiotic?
Used daily, this probiotic helps nourish the digestive environment, promote healthy gut bacteria, and encourage natural GLP-1 activity. These benefits may support appetite regulation, regular digestion, and overall metabolic wellness.Akkermansia muciniphila also supports the production of short-chain fatty acids, which are key compounds involved in gut lining maintenance and energy metabolism. -
What is Akkermansia muciniphila?
Akkermansia muciniphila is one of the naturally occurring gut microbes found in the human intestinal tract. It helps maintain the gut lining, supports a balanced microbiome, and contributes to the production of short-chain fatty acids—compounds linked to metabolic health and digestive function. -
How does Akkermansia support gut health?
Akkermansia helps maintain gut lining integrity and supports the natural diversity of gut bacteria, both of which are important for digestive wellness, nutrient absorption, and overall gut function.A healthier gut environment may also support processes tied to metabolism and immune balance—such as maintaining blood sugar stability, moderating fat storage, and supporting the gut’s role in immune signaling. -
Who should not take Akkermansia?
Anyone who is pregnant, nursing, managing a health condition, or taking medication should speak with their healthcare provider before using supplements that influence gut microbiota composition. -
How do I get Akkermansia naturally?
Foods that nourish your gut—like leafy greens, berries, flaxseeds, and polyphenol-rich options like green tea—may encourage Akkermansia growth naturally. -
What are the side effects of Akkermansia?
Most individuals tolerate Akkermansia-based products well. As with any supplement, responses vary. If you notice anything unexpected, consult your healthcare provider. -
How do I know if I need Akkermansia?
When the gut becomes imbalanced, it can affect how you digest food, absorb nutrients, and manage energy. This shift—sometimes called gut microbiota dysbiosis—may also influence appetite and weight over time.Adding a daily probiotic that supports gut barrier strength and microbial diversity can be a helpful step. A formula with Akkermansia muciniphila may help bring your gut back into balance. -
How do I increase my Akkermansia in my gut?
Eating more prebiotic-rich foods—such as onions, garlic, asparagus, oats, and legumes—can help nourish beneficial gut bacteria, including Akkermansia. These foods provide fiber that supports microbial activity.In addition to diet, a probiotic that includes Akkermansia muciniphila may help maintain microbial diversity and gut barrier function. -
Can Akkermansia help with weight management?
Akkermansia helps maintain a balanced gut microbiome, which may support metabolic function and appetite signaling—two factors that can influence body weight when paired with healthy lifestyle habits like diet and exercise. -
Does Akkermansia support weight loss?
Akkermansia muciniphila supports gut balance, which may influence factors linked to weight—such as appetite regulation, glucose tolerance, and how the body stores fat.While it's not intended for weight loss, maintaining healthy levels of Akkermansia may support metabolic wellness when combined with proper nutrition, regular activity, and other healthy habits. -
How does Akkermansia affect GLP-1?
Akkermansia supports gut lining health and microbiome balance—both of which influence how and when GLP-1 is naturally produced. While Akkermansia doesn’t directly increase GLP-1, a healthier digestive environment may support the body’s natural hormone activity. -
What hormone is GLP-1?
GLP-1, or glucagon-like peptide-1, is a natural hormone released by the gut in response to eating. It supports normal blood sugar regulation and may influence how full you feel after meals. -
How can I increase my GLP-1 hormone naturally?
You may encourage your body’s natural GLP-1 production through a combination of daily habits:- Eating high-fiber foods—like vegetables, legumes, and oats
- Eating a balanced diet that includes fermented or prebiotic foods
- Regular physical activity
- Getting adequate sleep
- Managing stress levels
- Avoiding excessive intake of highly processed or high-sugar foods
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Does GLP-1 support weight loss?
GLP-1 is a natural gut hormone released after eating. It helps regulate appetite signals and supports glucose tolerance, which may make it easier to maintain steady blood sugar levels and balanced eating patterns.While GLP-1 is not a weight loss solution on its own, it affects how the body responds to food. -
What foods contain GLP-1?
GLP-1 itself isn’t found in food—it’s a hormone your body produces in the gut after eating. However, certain whole foods can help support its natural release.Fiber-rich options like legumes, oats, fruits, and vegetables, along with fermented foods such as kimchi or yogurt, may help nourish gut microbes involved in GLP-1 signaling. -
Terms to know
Glossary of terms:- Akkermansia muciniphila: A naturally occurring bacterium found in the human intestinal tract. It helps support gut barrier integrity and contributes to a balanced gut microbiome.
- Gut health supplement: A dietary product made with ingredients like probiotics, prebiotics, or peptides that help maintain a balanced gut microbiome and support normal digestive function.
- Gut microbiome: The complete collection of genetic material from all the microorganisms in the gut microbiota. It plays a key role in gut and overall health.
- Gut barrier function: The gut lining’s ability to act as a selective barrier—allowing nutrients to pass while keeping potentially harmful substances out of the bloodstream.
- Human gut microbiota: The community of microorganisms, including bacteria, that live in the digestive tract and influence various functions such as digestion and immune response.
- Body Protective Compound-157 (BPC-157): A synthetic peptide compound that supports digestive tissue integrity. In supplement form, it's used to promote gut health and gastrointestinal balance.
- Salcaprozate sodium (SNAC): A delivery technology used to enhance the absorption of certain nutrients and compounds, particularly those that are less bioavailable in oral form.
- Sunfiber (galactomannan fiber): A soluble prebiotic fiber derived from guar beans. It feeds beneficial bacteria in the gut and supports regularity and digestive comfort.
- Short-chain fatty acids (SCFAs): Compounds produced when gut bacteria ferment dietary fiber. SCFAs, such as butyrate, help nourish gut lining cells and support metabolic activity.
- Glucagon-like peptide-1 (GLP-1): A gut-derived hormone released after eating. It supports blood sugar regulation and can influence feelings of fullness.
- Gut bacteria: Microorganisms that naturally reside in the human gastrointestinal tract. Some strains are beneficial and support digestive and immune functions.
- Intestinal microbiota: Another term for gut microbiota, referring to the microorganisms living in the intestines.
- Immune signaling: The process by which cells in the immune system communicate using chemical signals. In the gut, this helps coordinate the body’s response to microbes and maintain immune balance.
- Appetite signaling: The communication between the gut, brain, and hormones that helps regulate hunger and fullness cues, often influenced by nutrients, gut bacteria, and hormones like GLP-1.
- Glucose tolerance: The body’s ability to maintain normal blood sugar levels following a meal. It is influenced by hormones like GLP-1 and the state of the gut microbiota.
- Blood sugar regulation: The process by which the body maintains stable glucose levels. It involves hormones, diet, activity, and gut health.
- Diet-induced obese mice: A common preclinical research model where mice are fed a high-fat diet to study metabolic health, gut microbiota changes, and interventions like probiotics.
- Prebiotic foods: Fiber-rich foods that nourish beneficial gut bacteria. Examples include garlic, onions, oats, and asparagus.
- Probiotic supplement: A dietary supplement containing live microorganisms intended to support the balance of the gut microbiota.