Akkermansia
Prebiotic | Live Probiotic*
- Supports GLP-1 Production
- Promotes Metabolic Efficiency
- Aids in Optimizing Gut Barrier Integrity
- Promotes Leaner Body Composition
Active Ingredients: Akkermansia (Live Akkermansia muciniphila), Sunfiber® Prebiotic (Galactomannan Fiber)
Other Ingredients: Vegetable Capsule (Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
HOW
Take 1-2 capsules daily with water or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
1-2 Capsules
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Benefits
- Supports GLP-1 Production
- Promotes Metabolic Efficiency
- Aids in Optimizing Gut Barrier Integrity
- Promotes Leaner Body Composition
-
Ingredients
Active Ingredients: Akkermansia (Live Akkermansia muciniphila), Sunfiber® Prebiotic (Galactomannan Fiber)
Other Ingredients: Vegetable Capsule (Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
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How To Use
HOW
Take 1-2 capsules daily with water or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
1-2 Capsules
Formulation
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Akkermansia
- Found In
- Human Gut Microbiome
- Source
- Isolated live Akkermansia muciniphilia
- Benefits
- Digestive Support, Promotes GLP-1 Production
- Science
- 1403 Published Articles
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Sunfiber
- Found In
- Human Gut Microbiome
- Source
- Galactomannan/Hydrolyzed Guar Gum
- Benefits
- Gut Barrier Integrity, Digestive Support
- Science
- 196 Published Articles
Akkermansia Muciniphila
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OVERVIEW
Akkermansia muciniphila, a key element in the gut microbiome. plays a crucial role in both longevity and metabolism. Studies have revealed that Akkermansia not only contributes to longevity by promoting gut health and immune resilience but also plays an important role in optimizing metabolism.'1,2,3 The primary manner in which Akkermansia is involved in longevity is the role it plays in creating an ideal environment in the gut. This, ultimately, lends to its impact on metabolism, specifically the production of glucagon-like peptide 1 (GLP-1), a specialized hormone which serves as a central player in metabolic health.4 At its core, the role of Akkermansia in promoting longevity is driven by this optimization of metabolism via GLP-1.
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INGREDIENTS
GUT HEALTH AND LONGEVITY
Akkermansia muciniphila has been shown to play an important role in promoting gut health, and thus, longevity through multiple mechanisms. First, Akkermansia muciniphila thrives on mucin and utilizes it as a source of energy. As Akkermansia consumes mucin, it stimulates the production of additional mucin by epithelial cells. This process of "mucin making" leads to the reinforcement of the intestinal wall. which is essential for maintaining gut health and overall well-being.5 Additionally, Akkermansia has been shown to promote short chain fatty acids, which further support the gut's immune defenses by inhibiting the invasion of potentially harmful bacteria.6 These combined effects create an environment conducive to a balanced gut microbiota and optimal gut function. which are key factors in supporting longevity and overall well-being.
METABOLISM AND GLP-1 PRODUCTION
In terms of metabolic optimization. Akkermansia muciniphila demonstrates remarkable capabilities, particularly in increasing the production of glucagon-like peptide 1 (GLP-1). GLP-1 is an incretin hormone that plays a crucial role in regulating glucose metabolism and insulin secretion.• Akkermansia promotes GLP-1 production through several pathways. First, it stimulates enteroendocrine cells in the gut to release GLP-1 in response to nutrient intake. Second. when Akkermansia provides aid to gut barrier function, it has the potential to mitigate metabolic endotoxemia, which can further stimulate GLP-1 secretion. Finally, as mentioned previously, Akkermansia produces short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate during fermentation, which have been shown to support healthy GLP-1 levels.6 The collective impact of these mechanisms results in the body's ability to support glucose tolerance and insulin sensitivity·7•8 as well as overall metabolic regulation, ultimately allowing for healthier fat metabolism and more effective means to achieving lean body composition and browning white fat.
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REFERENCES
1. Ou yang J, Lin J, lsnard S, Fombuena B, Peng X, Marette A, Routy B, Messaoudene M, Chen Y , Routy JP . Front lmmunol. 2020 Apr 9;11:645.
2. Chelakkot c .. Choi Y .. Kim D.-K .. Park H.T .. Ghim J .. Kwon Y .. Jeon J .. Kim M.-s .. Jee Y .-K .. Gho Y .S .. et al. Exp. Mo/. Med. 2018;50:e450.
3. Bae M .. Cassilly G.D .. Liu x .. Park s.-M., Tusi B.K.. Chen x .. Kwon J .. Filipcfk P .. Bolze A.S .. Liu z .. et al. Nature. 2022;608:168-173.
4. Y oon H.S .. Cho C.H .. Y un M.S .. Jang SJ .. Y ou HJ .. Kim J.-H .. Han D .. Cha K.H .. Moon S.H .. Lee K., et al. Nat Microbiol. 2021;6:563-573.
5. Kim S .. Shin Y .-c .. Kim T.-Y .. Kim Y .. Lee Y .-s .. Lee S.-H., Kim M.-N., OE., Kim K.S .. Kweon M.-N. Gut Microbes. 2021;13:1892441.
6. Rodrigues VF, Elias-Oliveira J, Pereira fs. Pereira JA. Barbosa SC, Machado MSG, Carlos D. Front lmmunol. 2022 Jul 7;13:934695.
7. Depommier C., Everard A., Druart C .. Plovier H .. V an Hui M .. Vieira-Silva S., Fa/ony G .. Raes J., Maiter D., Delzenne N.M .. et al. Nat. Med. 2019;25:1096-1103.
8. Wang z. Cui S, Zhang T. Wang W, Li J, Chen YQ. Zhu SI. mSystems. 2023 Oct 26;8(5):e0057323.
9. Everard A., Belzer C., Geurts L, Ouwerkerk J.P ., Druart C., Binde/s LB., Guiot Y ., Derrien M., Muccioli G.G., Delzenne N.M., et al. Natl. Acad. Sci. USA. 2013;110:9066-9071.
10. Deng L. Ou z .. Huang D .. Li c .. Luz .. Liu W .. Wu F .. Nong c .. Gao J .. Peng Y. Microb. Pathog. 2020;147:104353.
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| Ingredients | Amount Per Serving |
| Akkermansia (Live Akkermansia muciniphila) | 500 million AFU |
| Sunfiber Prebiotic (Galactomannan Fiber) | 250mg |
Other Ingredients: Vegetable Capsule
(Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
Professional Information
People Requiring:
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Metabolic and GLP-1 Support
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Gut Barrier Integrity Maintenance
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Longevity Protocols
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Digestive Health Support
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FAQs
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Why is maintaining a healthy gut important?
A healthy gut is essential for overall health—it supports the digestive system, immune response, and even mental well-being. A balanced gut microbiome that includes probiotic bacteria like Akkermansia muciniphila helps break down food and produce nutrients that support human health. It also helps maintain the integrity of the gut lining, which prevents harmful substances, such as excess stomach acid, from damaging the body’s systems.A strong gut barrier supports regular digestion, reducing issues like loose stools while also helping the immune system respond effectively to daily challenges. Maintaining healthy Akkermansia levels may promote metabolic balance, support a resilient gut barrier, and contribute to weight management. -
What is InfiniWell Akkermansia?
InfiniWell Akkermansia is a dietary supplement containing live Akkermansia muciniphila—a keystone strain known to support gut barrier function and metabolic health. It also includes Sunfiber Prebiotic to help feed beneficial gut bacteria. Together, these ingredients work to promote a healthy gut microbiome, support insulin sensitivity, and help maintain a leaner body composition.This supplement is intended as a dietary product—not to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider for medical advice. -
How does Akkermansia support gut health?
InfiniWell Akkermansia features live Akkermansia muciniphila, a naturally occurring bacterium found in the human gut. Research suggests that Akkermansia supports the gut barrier by producing short-chain fatty acids (SCFAs) that help maintain the integrity of the gut lining. This contributes to better digestion and reduced bloating and may help with managing occasional digestive discomfort.A strong gut barrier supports overall immune response, helping healthy people maintain wellness throughout life. Additionally, Akkermansia may contribute to a healthier metabolic profile, supporting normal blood sugar levels and weight management.
A balanced gut microbiome is nourished by food that promotes the growth of beneficial bacteria like Akkermansia. Examples include foods high in dietary fiber and prebiotics, such as asparagus, garlic, leeks, onions, bananas, whole grains, and legumes. If dietary intake is not enough, supplements—including high-quality probiotic supplements containing Akkermansia muciniphila—may provide additional support. -
What are the key benefits of InfiniWell Akkermansia?
InfiniWell's Akkermansia Probiotic is designed to support your gut health and metabolic wellness naturally.Key benefits include:- Supports GLP-1 production: Helps regulate appetite and metabolism
- Promotes metabolic efficiency: Supports healthy weight management and balanced blood sugar levels
- Aids in optimizing gut barrier integrity: Contributes to a strong gut lining that may help protect against toxins and support immune function
- Promotes leaner body composition: May support fat metabolism and aid in maintaining a healthy body weight
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How should I take InfiniWell Akkermansia?
Take 1–2 Akkermansia capsules daily with water, ideally on an empty stomach or as directed by your healthcare provider. Consistent daily use may offer the best support for gut health and metabolic function. -
How long does it take for InfiniWell Akkermansia to work?
Individual experiences may vary, but some users notice digestive or metabolic benefits within a few weeks. Consistent daily use over 2–3 months may provide more noticeable results, such as positive changes in gut barrier function and metabolic profile.Factors like diet, lifestyle, and baseline gut health can influence the speed of results. -
Who should consider taking InfiniWell Akkermansia?
InfiniWell Akkermansia is suitable for adults looking to support a healthy gut microbiome, metabolic function, and immune response.It may be especially helpful for:
- Those with low levels of Akkermansia bacteria in their gut
- Individuals seeking to support insulin sensitivity and maintain a healthy weight
- Anyone looking to promote gut barrier function for overall digestive health
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What makes InfiniWell Akkermansia different from other probiotic supplements?
InfiniWell Akkermansia focuses on a keystone strain—Akkermansia muciniphila—which helps maintain a healthy gut barrier and supports metabolic health. Unlike many probiotics, this supplement contains a live strain of Akkermansia for maximum efficacy.It’s also:- Third-party tested for quality and purity
- Free from unnecessary additives—no artificial fillers, stimulants, or hidden blends
- Manufactured in a GMP-certified facility to ensure consistent potency
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Can InfiniWell Akkermansia be combined with other supplements?
Yes! Our Akkermansia supplement can complement many other gut health and wellness supplements, including:- Magnesium: To support regular bowel movements and digestive health
- Vitamin D: For immune function and gut health
- Other probiotic strains: Such as Lactobacillus or Bifidobacterium species to support a diverse gut microbiome
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Is InfiniWell Akkermansia safe?
Yes, InfiniWell Akkermansia is formulated with quality and safety in mind. It is:- Physician-formulated
- Third-party tested
- Produced in a GMP-certified facility
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Can InfiniWell Akkermansia help with weight management?
Yes, research suggests that Akkermansia muciniphila may support leaner body composition by influencing metabolic pathways involved in fat metabolism and appetite regulation.While not a weight loss product, InfiniWell's Akkermansia muciniphila supplement may help support your weight management goals when combined with a healthy diet and lifestyle. -
What is pasteurized Akkermansia muciniphila, and how is it different from live Akkermansia?
Pasteurized Akkermansia muciniphila is Akkermansia muciniphila that has been heat-treated to inactivate the bacteria while preserving its key structural components and potential benefits. In contrast, live Akkermansia muciniphila contains active, living bacteria that continue to grow and interact with the gut microbiome.Both forms have shown promise in research for supporting gut barrier integrity, metabolic health, and a balanced digestive system. Pasteurized Akkermansia muciniphila offers added stability and may be easier to incorporate into certain supplement forms, while live Akkermansia can directly integrate with the gut microbiome for continuous growth and interaction.
InfiniWell Akkermansia uses the live strain to naturally support overall health, immune system function, and a healthy gut barrier—helping you maintain gut wellness every day. -
Glossary of terms
Terms to know:- Akkermansia muciniphila: A naturally occurring bacterium in the human gut, known for supporting gut barrier integrity and metabolic health.
- Gut barrier function: The protective lining of the gut that helps keep harmful substances out of the bloodstream.
- GLP-1: A hormone involved in appetite and glucose regulation.
- GMP-certified facility: A manufacturing facility that follows Good Manufacturing Practices to ensure product quality.
- Metabolic function: The body’s processes that convert food into energy and support essential functions such as blood sugar balance and fat metabolism.
- Insulin sensitivity: How effectively the body responds to insulin, which helps regulate blood sugar levels.
- Prebiotic: A type of fiber that feeds beneficial gut bacteria.
- Probiotic: Live microorganisms that support a healthy gut microbiome.
- Sunfiber Prebiotic: A dietary fiber derived from guar gum, known for its gentle digestive support.
- Short-chain fatty acids (SCFAs): Compounds like acetate and propionate produced by gut bacteria that support gut barrier function and metabolic health.
- Keystone strain: A beneficial gut microbe that supports microbiome balance and health, such as Akkermansia muciniphila.
- Stomach acid: Digestive fluid that helps break down food and protect against harmful microbes; a healthy gut barrier helps manage exposure to stomach acid.
- Microbiome diversity: The variety of microorganisms in the gut, associated with a more resilient and balanced digestive environment.