The Ultimate Longevity Duo: Akkermansia & BPC-157

There are many supplement “powerhouse duos” that, when taken together, can improve a person’s overall health. Vitamin C and zinc help boost the immune system and can decrease your chances of catching a cold. Calcium and magnesium can help improve bone and tooth health. But when it comes to longevity, taking the peptide BPC-157 along with probiotic Akkermansia muciniphila can have positive effects on gut health and, ultimately, longevity.

BPC-157 strengthens the gut barrier, sealing off potential leaks and protecting against harmful substances, and when combined with Akkermansia muciniphila, the two work synergistically to fortify the gut lining, support digestion and enhance overall health.

Let’s break down this dynamic duo and learn the longevity benefits of taking this peptide and probiotic together.

BPC-157
BPC-157 has been shown to strengthen the body’s intestinal mucosal barrier, which plays a critical role in maintaining gut health. But what does BPC-157 do exactly? In simple terms, BPC-157 acts as a membrane stabilizer, or a defender of your gut, strengthening its defenses and keeping it healthy. It helps to seal off potential leaks in the gut by promoting the expression of tight junctions, which act like seals between the cells of the intestinal lining to prevent harmful substances from passing through and causing damage.1

Additionally, BPC-157 protects against harmful substance translocation and damage caused by oxidative stress, which can further compromise gut health and, in turn, longevity.2 By reducing permeability and blocking the translocation of harmful substances, BPC-157 helps to maintain the integrity of the gut barrier.

AKKERMANSIA MUNCINIPHILA
Akkermansia muciniphila, or Akkermansia, is a friendly bacteria that resides in the gut and plays a crucial role in maintaining gut health by breaking down the mucus lining and supporting a balanced gut environment. 

Akkermansia also aids in maintaining a healthy body weight by improving the metabolism. Research has shown that higher levels of Akkermansia are associated with improved metabolic health and and is currently one of modern medicine's most prominent players in weight management.3 Similarly, Akkermansia has been linked to enhanced insulin sensitivity, meaning it helps the body respond better to insulin, which is crucial for regulating blood sugar levels.4 

THE ULTIMATE LONGEVITY DUO
As we covered, Akkermansia can work wonders by modulating metabolism, enhancing insulin sensitivity and applying anti-inflammatory effects — all essential for overall health. Where BPC-157 steps in as the ideal partner is by improving the gut barrier’s integrity therefore creating an ideal environment for Akkermansia colonization and allowing it to unleash its full potential. BPC-157 also allows Akkermansia to unlock its full anti-aging capabilities, including its ability to enhance healthspan and delay age-related decline in physiological functions.5

By incorporating supplements featuring BPC-157 and Akkermansia muciniphila into your daily routine, you can harness the comprehensive benefits of this synergistic alliance to create a powerful 1-2 punch for sustained gut health, metabolic regulation, and longevity promotion.

SOURCES:

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710746/
2. https://regendoctors.com/how-does-bpc-157-work/#:~:text=Protecting%20against%20cell%20death%3A%20BPC,promote%20cell%20survival%20and%20healing.
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583218/
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300896/
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676789/