The Longevity Probiotic: Unraveling the Benefits of Akkermansia

The gut microbiota is incredibly diverse, consisting of trillions of microorganisms, each with its own distinct characteristics and functions. However, in this vast labyrinth of gut microbiota, one bacteria stands out: Akkermansia muciniphila, or Akkermansia for short. 

With its potential as the "longevity probiotic" gaining traction, researchers have begun to unravel Akkermansia’s many benefits and abilities when it comes to promote healthy aging while also warding off age-related ailments.1 The following are six key ways Akkermansia may contribute to longevity:

Fights Against Obesity
Studies have found that higher levels of Akkermansia in the gut are associated with a lower risk of obesity.2 But how does it do this? Research has shown that Akkermansia may be able to help regulate metabolism, improve insulin sensitivity and dial down inflammation, which keeps weight in check and helps the body function optimally.3

Improves the Gut Barrier
Imagine your gut as a fortress, with the intestinal mucosal barrier acting as its sturdy walls. Akkermansia plays the role of guardian of your gut, strengthening this intestinal mucosal barrier, preventing leakage of harmful substances and reducing inflammation — all of which can help you live a longer and healthier life.

Balances the Immune System
The immune system functions as a complex network, with each component playing a critical role in maintaining balance within the body. Akkermansia has been shown to modulate the immune system, promote a balanced inflammatory response and potentially reduce the chronic inflammation that’s typically associated with aging.

Shields Against Age-Related Diseases
Studies have linked higher Akkermansia levels to a reduced risk of conditions such as type 2 diabetes, cardiovascular disease and certain cancers, all of which are major contributors to age-related morbidity and mortality.4

Promotes Gut Microbiome Diversity
Your gut microbiome is a bustling ecosystem that’s teeming with diverse life forms. Akkermansia can help maintain that healthy gut ecosystem, ensuring that it remains a thriving hub of microbial activity.5 A balanced gut microbiome is not only key to digestive health but is also associated with better health outcomes.

Nurtures Anti-Aging Effects
Aging is inevitable, but that doesn't mean it can't be done gracefully. In animal studies, supplementation with Akkermansia, or increasing its abundance, has been shown to extend lifespan and delay age-related decline in physiological functions.6

 From battling obesity to protecting against age-related diseases, this bacterium packs a powerful punch, and a healthy gut translates to a healthy, longer life. To maximize the effects of Akkermansia, consult your physician about incorporating a supplement with this key ingredient into your daily regime.

SOURCES:

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676789/
2. https://pubmed.ncbi.nlm.nih.gov/33110437/#:~:text=Background%3A%20Gut%20bacteria%20Akkermansia%20has,verified%20in%20a%20generalized%20population.
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161007/
4. https://www.mdpi.com/2075-1729/13/6/1247#:~:text=Accumulating%20evidence%20indicated%20Akkermansia%20as,enrichment%20may%20be%20not%20beneficial.
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401025/
6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676789/