Akkermansia
Prebiotic | Live Probiotic*
- Supports GLP-1 Production
- Promotes Metabolic Efficiency
- Aids in Optimizing Gut Barrier Integrity
- Promotes Leaner Body Composition
Active Ingredients: Akkermansia (Live Akkermansia muciniphila), Sunfiber® Prebiotic (Galactomannan Fiber)
Other Ingredients: Vegetable Capsule (Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
HOW
Take 1-2 capsules daily with water or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
1-2 Capsules
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Benefits
- Supports GLP-1 Production
- Promotes Metabolic Efficiency
- Aids in Optimizing Gut Barrier Integrity
- Promotes Leaner Body Composition
-
Ingredients
Active Ingredients: Akkermansia (Live Akkermansia muciniphila), Sunfiber® Prebiotic (Galactomannan Fiber)
Other Ingredients: Vegetable Capsule (Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
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How To Use
HOW
Take 1-2 capsules daily with water or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
1-2 Capsules
Akkermansia
Formulation
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Akkermansia
- Found In
- Human Gut Microbiome
- Source
- Isolated live Akkermansia muciniphilia
- Benefits
- Digestive Support, Promotes GLP-1 Production
- Science
- 1403 Published Articles
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Sunfiber
- Found In
- Human Gut Microbiome
- Source
- Galactomannan/Hydrolyzed Guar Gum
- Benefits
- Gut Barrier Integrity, Digestive Support
- Science
- 196 Published Articles
Akkermansia Muciniphila
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OVERVIEW
Akkermansia muciniphila, a key element in the gut microbiome. plays a crucial role in both longevity and metabolism. Studies have revealed that Akkermansia not only contributes to longevity by promoting gut health and immune resilience but also plays an important role in optimizing metabolism.'1,2,3 The primary manner in which Akkermansia is involved in longevity is the role it plays in creating an ideal environment in the gut. This, ultimately, lends to its impact on metabolism, specifically the production of glucagon-like peptide 1 (GLP-1), a specialized hormone which serves as a central player in metabolic health.4 At its core, the role of Akkermansia in promoting longevity is driven by this optimization of metabolism via GLP-1.
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INGREDIENTS
GUT HEALTH AND LONGEVITY
Akkermansia muciniphila has been shown to play an important role in promoting gut health, and thus, longevity through multiple mechanisms. First, Akkermansia muciniphila thrives on mucin and utilizes it as a source of energy. As Akkermansia consumes mucin, it stimulates the production of additional mucin by epithelial cells. This process of "mucin making" leads to the reinforcement of the intestinal wall. which is essential for maintaining gut health and overall well-being.5 Additionally, Akkermansia has been shown to promote short chain fatty acids, which further support the gut's immune defenses by inhibiting the invasion of potentially harmful bacteria.6 These combined effects create an environment conducive to a balanced gut microbiota and optimal gut function. which are key factors in supporting longevity and overall well-being.
METABOLISM AND GLP-1 PRODUCTION
In terms of metabolic optimization. Akkermansia muciniphila demonstrates remarkable capabilities, particularly in increasing the production of glucagon-like peptide 1 (GLP-1). GLP-1 is an incretin hormone that plays a crucial role in regulating glucose metabolism and insulin secretion.• Akkermansia promotes GLP-1 production through several pathways. First, it stimulates enteroendocrine cells in the gut to release GLP-1 in response to nutrient intake. Second. when Akkermansia provides aid to gut barrier function, it has the potential to mitigate metabolic endotoxemia, which can further stimulate GLP-1 secretion. Finally, as mentioned previously, Akkermansia produces short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate during fermentation, which have been shown to support healthy GLP-1 levels.6 The collective impact of these mechanisms results in the body's ability to support glucose tolerance and insulin sensitivity·7•8 as well as overall metabolic regulation, ultimately allowing for healthier fat metabolism and more effective means to achieving lean body composition and browning white fat.
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REFERENCES
1. Ou yang J, Lin J, lsnard S, Fombuena B, Peng X, Marette A, Routy B, Messaoudene M, Chen Y , Routy JP . Front lmmunol. 2020 Apr 9;11:645.
2. Chelakkot c .. Choi Y .. Kim D.-K .. Park H.T .. Ghim J .. Kwon Y .. Jeon J .. Kim M.-s .. Jee Y .-K .. Gho Y .S .. et al. Exp. Mo/. Med. 2018;50:e450.
3. Bae M .. Cassilly G.D .. Liu x .. Park s.-M., Tusi B.K.. Chen x .. Kwon J .. Filipcfk P .. Bolze A.S .. Liu z .. et al. Nature. 2022;608:168-173.
4. Y oon H.S .. Cho C.H .. Y un M.S .. Jang SJ .. Y ou HJ .. Kim J.-H .. Han D .. Cha K.H .. Moon S.H .. Lee K., et al. Nat Microbiol. 2021;6:563-573.
5. Kim S .. Shin Y .-c .. Kim T.-Y .. Kim Y .. Lee Y .-s .. Lee S.-H., Kim M.-N., OE., Kim K.S .. Kweon M.-N. Gut Microbes. 2021;13:1892441.
6. Rodrigues VF, Elias-Oliveira J, Pereira fs. Pereira JA. Barbosa SC, Machado MSG, Carlos D. Front lmmunol. 2022 Jul 7;13:934695.
7. Depommier C., Everard A., Druart C .. Plovier H .. V an Hui M .. Vieira-Silva S., Fa/ony G .. Raes J., Maiter D., Delzenne N.M .. et al. Nat. Med. 2019;25:1096-1103.
8. Wang z. Cui S, Zhang T. Wang W, Li J, Chen YQ. Zhu SI. mSystems. 2023 Oct 26;8(5):e0057323.
9. Everard A., Belzer C., Geurts L, Ouwerkerk J.P ., Druart C., Binde/s LB., Guiot Y ., Derrien M., Muccioli G.G., Delzenne N.M., et al. Natl. Acad. Sci. USA. 2013;110:9066-9071.
10. Deng L. Ou z .. Huang D .. Li c .. Luz .. Liu W .. Wu F .. Nong c .. Gao J .. Peng Y. Microb. Pathog. 2020;147:104353.
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| Ingredients | Amount Per Serving |
| Akkermansia (Live Akkermansia muciniphila) | 500 million AFU |
| Sunfiber Prebiotic (Galactomannan Fiber) | 250mg |
Other Ingredients: Vegetable Capsule
(Hypromellose, Gellan Gum), Microcrystalline Cellulose, Magnesium Stearate
Professional Information
People Requiring:
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Metabolic and GLP-1 Support
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Gut Barrier Integrity Maintenance
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Longevity Protocols
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Digestive Health Support
Practitioners Recommend
Akkermansia Probiotic Capsules: FAQs
Have more questions? We have answers
InfiniCare—your personal concierge for longevity. Our team of experts, including our on-staff physician, are standing by to ensure world-class service.
Call Us 1-888-819-4640
Our team is located in Dallas, TX, USA
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Why is maintaining a healthy gut important?
The gut microbiome plays an important role in overall wellness. It contains trillions of microorganisms that participate in digestion, nutrient processing, and immune system activity.A balanced microbiome supports the digestive system and helps maintain the gut barrier, the protective lining of the digestive tract that helps keep unwanted substances from entering the bloodstream.
When beneficial microbes are present in healthy amounts, the gut environment tends to remain more stable. This balance supports digestive comfort, efficient nutrient use, and overall well-being. -
What is InfiniWell Akkermansia?
InfiniWell Akkermansia is a dietary supplement that contains live Akkermansia muciniphila, a bacterium naturally present in the human gut.Research has identified this organism as an important contributor to a balanced gut microbiome. InfiniWell’s formula pairs this strain with Sunfiber prebiotic to help nourish beneficial bacteria already present in the digestive system.
Together, these ingredients are designed to support microbiome balance and everyday digestive wellness.
InfiniWell Akkermansia is intended as a dietary supplement and not to diagnose, treat, cure, or prevent any disease. -
How does Akkermansia support gut health?
Akkermansia muciniphila naturally lives in the mucus layer of the digestive tract. Emerging research suggests that this bacterium is associated with maintaining the gut barrier and supporting a balanced microbiome.Scientists also study its relationship with compounds produced during normal microbial activity in the gut, such as short-chain fatty acids. These compounds are connected with digestive balance and overall microbiome health.
When the gut microbiome remains diverse and balanced, it can support digestive comfort and help the body maintain its natural processes.
Many everyday foods support the growth of beneficial bacteria, including fiber-rich vegetables and prebiotic foods such as garlic, onions, asparagus, bananas, legumes, and whole grains. For additional microbiome support, probiotic supplements containing strains like Akkermansia muciniphila may be a convenient option.
Research on this strain continues to develop, and individual experiences can vary. -
What are the key benefits of InfiniWell Akkermansia?
InfiniWell Akkermansia is formulated to support gut microbiome balance and overall wellness.Potential benefits include:- Gut microbiome balance support: Provides the Akkermansia muciniphila strain along with prebiotic fiber to help nourish beneficial bacteria.
- Gut barrier function support: Emerging research suggests Akkermansia may be associated with maintaining gut lining strength.
- Digestive wellness support: A balanced microbiome can contribute to digestive comfort and balance.
- Metabolic wellness support: Healthy microbiome activity is connected with broader metabolic processes involved in how the body uses nutrients.
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How should I take InfiniWell Akkermansia?
The suggested use is 1–2 capsules daily with water, preferably before meals.As with any supplement, speak with a qualified healthcare professional if you have questions about adding it to your routine. -
How long does it take to notice results?
Everyone’s microbiome is unique, so individual experiences can vary.Some people notice changes in digestive comfort within a few weeks. For others, maintaining consistent use over several months may provide a clearer sense of how the supplement fits into their wellness routine.
Diet, lifestyle, and overall microbiome balance can all influence how quickly someone notices changes. -
Who may consider taking InfiniWell Akkermansia?
InfiniWell Akkermansia may be suitable for adults interested in supporting their gut microbiome and overall wellness.It may be especially appealing for those who:
- Want to support microbiome diversity
- Are looking for additional digestive wellness support
- Are interested in emerging research on Akkermansia muciniphila
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What makes InfiniWell Akkermansia different from other probiotic supplements?
Many probiotic products focus on common strains such as Lactobacillus or Bifidobacterium. InfiniWell Akkermansia centers on a different organism that has gained attention in recent microbiome research.The formula features:
- Live Akkermansia muciniphila
- Sunfiber prebiotic to help nourish beneficial microbes
- Third-party testing for quality
- Manufacturing in a GMP-certified facility
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Can InfiniWell Akkermansia be combined with other supplements?
Many people include probiotic supplements as part of a broader wellness routine.InfiniWell Akkermansia may be used alongside other supplements that support general wellness, such as vitamins, minerals, or other probiotics.
If you take medications or have health concerns, speak with a healthcare professional before combining supplements. -
Is InfiniWell Akkermansia safe?
InfiniWell Akkermansia is manufactured with quality and safety standards in mind. The product is:- Third-party tested
- Manufactured in a GMP-certified facility
- Formulated for daily use by adults
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Can Akkermansia support weight management goals?
Research on the gut microbiome has explored how certain bacteria relate to metabolic processes involved in how the body uses nutrients and stores energy. Emerging studies have observed associations between Akkermansia muciniphila and aspects of metabolic wellness, which has led to growing interest in this strain.Because microbiome balance can influence broader physiological processes, maintaining healthy microbial diversity may support overall wellness and metabolic balance.
That said, supplements are only one piece of the picture. Balanced nutrition, regular physical activity, and good sleep habits remain the most important foundations for long-term weight management. -
What is pasteurized Akkermansia muciniphila, and how is it different from live Akkermansia?
Pasteurized Akkermansia muciniphila refers to bacteria that have been heat-treated to inactivate the organism while preserving certain structural components that researchers study.Live Akkermansia muciniphila, on the other hand, contains active microorganisms that can interact with the gut microbiome after consumption.
Both forms have been explored in scientific research related to microbiome balance and metabolic wellness. Each approach offers different advantages depending on the product formulation.
InfiniWell Akkermansia contains the live strain, which is intended to integrate with the existing gut microbiome as part of a daily wellness routine. -
Disclaimer
This information is provided for general educational purposes only and is not medical advice. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Before adding a new supplement or adjusting your wellness routine, consider speaking with a qualified healthcare professional.