CALMA

This formula is designed to support relaxation, mental clarity, and overall cognitive well-being. It combines three key ingredients—L-TeaActive^®, BaCognize^®, and DHH-B (Dihydrohonokiol)—that work synergistically to promote calm, support cognitive function, and maintain a balanced stress response. Each ingredient has been carefully selected for its unique properties and potential to contribute to a sense of tranquility and mental vitality.

L-TeaActive^®

L-TeaActive^® is a source of L-theanine, a naturally occurring amino acid derived from the leaves of Camellia sinensis. L-theanine has been studied for its role in promoting alpha brain wave activity, which is associated with a relaxed yet alert mental state. Research indicates that L-theanine may support focus, mental clarity, and attention span.^1,2

Additionally, L-theanine is thought to influence neurotransmitter activity, supporting a positive mood and overall sense of well-being. By promoting the activity of inhibitory neurotransmitters, L-theanine may also support relaxation and restful sleep. This combination of benefits makes L-TeaActive^® a versatile ingredient for cognitive and stress support.

BaCognize^®

BaCognize^® is an extract of Bacopa monnieri, a plant traditionally used to support cognitive health. Studies suggest that it may help maintain memory, mental clarity, and focus. BaCognize^® has been shown to influence neurotransmitters such as acetylcholine, serotonin, and dopamine, which are involved in mood regulation, attention, and cognitive function.³

This ingredient also has antioxidant properties that help protect neurons from oxidative stress and support neuronal resilience. By promoting synaptic plasticity, BaCognize^® may enhance communication between brain cells, supporting cognitive performance. Furthermore, it has been studied for its ability to support the stress response system, helping maintain cognitive function during periods of stress.⁴

DHH-B

Dihydrohonokiol (DHH-B) is derived from Magnolia officinalis and is known for its relaxation-supporting properties. It is thought to enhance GABAergic activity by interacting with GABA receptors in the brain, promoting calmness and relaxation.⁵

DHH-B also exhibits antioxidant properties, which help protect neurons and support cellular health. By reducing oxidative stress in sensitive brain tissues, it may contribute to neuroprotection and overall cognitive function.^6,7

1. White DJ, de Klerk S, et al. ANutrients. 2016;8(1):53. doi:10.3390/nu8010053.

2. Higashiyama A, Htay HH, et al., Journal of Functional Foods. 2011; doi:10.1016/j.j.2011.03.009.

3. Lopresti, A. L., Smith, S. J., Ali, S., Metse, A. P., Kalns, J., & Drummond, P. D. (2021). Journal of Functional Foods, 85, 104671. ISSN 1756-4646. https://doi.org/10.1016/j.jff.2021.104671.

4. Best T, Clarke C, Nuzum N, Teo WP. Nutr Neurosci. 2021 Nov;24(11):873-884. doi: 10.1080/1028415X.2019.1690288. Epub 2019 Nov 18. PMID: 31736428.

5. Maruyama Y, Kuribara H, Kishi E, Weintraub ST, Ito Y. J Pharm Pharmacol. 2001 May;53(5):721-5. doi: 10.1211/0022357011775848. PMID: 11370711. https://doi.org/10.1211/0022357011775848

6. Kuribara H, Kishi E, Kimura M, Weintraub ST, Maruyama Y. Pharmacol Biochem Behav. 2000 Nov;67(3):597-601. doi: 10.1016/s0091-3057(00)00401-9. PMID: 11164091. https://doi.org/10.1016/s0091-3057(00)00401-9

7. Woodbury, A., Yu, S. P., Wei, L., & Garcia, P. (2013). Frontiers in Neurology, 4, 130. https://doi.org/10.3389/fneur.2013.00130