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Complete Product InformationRecent Clinical Breakthroughs
InfiniWell is constantly researching the latest findings of clinical research to further develop solutions for practitioners and patients alike. Below are some of the most recent clinical breakthroughs that helped inform our formulary.
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Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study
Sleep deficit or poor sleep leads to ill-health, whereas sleep deprivation for longer periods of time increases the risk of developing adverse conditions associated with poor quality of life, and high socioeconomic impact. The treatments for sleep disturbances include melatonin and over-the-counter medicines like diphenhydramine and doxylamine, all of which have negative side effects. Valerian (Valeriana officinalisL.) is a traditional herb and the most preferred alternate sleep solution to manage sleep complaints.
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A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults
Non-restorative sleep (NRS) affects 10% people worldwide, leading to poor sleep quality, as well as physical and cognitive fatigue. This is the first human study in which an extract of ashwagandha (Withania somnifera Dunal L.) was evaluated for effects in improving overall sleep quality in subjects with NRS.
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GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage
Determinants of length of life are not well understood, and therefore increasing lifespan is a challenge. Cardinal theories of aging suggest that oxidative stress (OxS) and mitochondrial dysfunction contribute to the aging process, but it is unclear if they could also impact lifespan. Glutathione (GSH), the most abundant intracellular antioxidant, protects cells from OxS and is necessary for maintaining mitochondrial health, but GSH levels decline with aging. Based on published human studies where we found that supplementing glycine and N-acetylcysteine (GlyNAC) improved/corrected GSH deficiency, OxS and mitochondrial dysfunction, we hypothesized that GlyNAC supplementation could increase longevity.
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Lutein/zeaxanthin isomers regulate neurotrophic factors and synaptic plasticity
This study was conducted to elucidate the effects of lutein/zeaxanthin isomers (L/Zi) on lipid metabolism, oxidative stress, NF-κB/Nrf2 pathways, and synaptic plasticity proteins.
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A Combination of Caffeine, TeaCrine® (Theacrine), and Dynamine® (Methylliberine) Increases Cognitive Performance and Reaction Time Without Interfering With Mood in Adult Male Egamers
Background Involvement in video game activities and competitive video gaming (esports) is a rapidly growing field. Moreover, there is a marked interest in identifying nutritional supplements to safely improve egamer performance. Methodology We conducted a repeated-measure, randomized crossover study to compare the effects of caffeine (125 mg), caffeine (125 mg) + Dynamine® (75 mg) + TeaCrine® (50 mg) (CDT), and matched placebo across three testing sessions (one week apart) among 50 young male egamers.
Insights
View More InsightsLongevity 101 Pt. 1
Introduction Longevity, the desire to extend our lifespan while preserving health and vitality, has been a fascination throughout human history. In the quest for longevity, medical science has made significant strides, unveiling the roles of cellular processes, senescent cells, mitochondrial function, and telomere health in the aging process. Alongside these breakthroughs, natural compounds have emerged as promising contenders in supporting healthy aging. This article delves into the cellular...
Rejuvenating Through the Night: Unveiling the Glymphatic System, Shode...
In order to fully understand the role of sleep as it relates to aging, its necessary to embark on an in-depth exploration of the intricate interplay between sleep, aging, and the potential therapeutic utility of a novel form of Ashwagandha with the highest concentration of active constituent that has shown to be the best option for sleep and aging support. In this comprehensive analysis, we will systematically dissect the various phases of sleep, encompassing the essential attributes of REM a...
Cardio Prime+ Product Overview
Cardiovascular and metabolic health are multi-faceted systems that require a holistic approach in order to provide authentic, effective support. More often than not, two areas that are overlooked are 1. energy production and 2. glucose metabolism. The connection between heart health and these two additional factors is very well established and the data continues confirming as much. So with these undeniably important elements layered on top of more ‘tried and true’ ingredients that research...
L-Ergothioneine: The Mitochondrial Marvel
L-ergothioneine is a naturally occurring amino acid derivative that accumulates within cells, particularly in mitochondria. Mitochondria are cellular organelles known as the powerhouses of the cell, responsible for generating energy in the form of adenosine triphosphate (ATP) through oxidative phosphorylation. The accumulation of L-ergothioneine within the mitochondria is due to a specific transporter protein known as OCTN1 (organic cation/carnitine transporter 1). This transporter is respons...
Cultivating Longevity Through Optimized Digestion: Unraveling the Role...
Recent advances in microbiology have led to the recognition of the gut microbiota as an essential component contributing to the aging process. The gut microbiota is a diverse ecosystem of microorganisms residing in the gastrointestinal tract that profoundly influences host health. This journal entry aims to explore the mechanisms by which the gut microbiota influences aging and potential interventions for healthier aging, drawing on relevant scientific literature. Gut Microbiota Composition a...
Harnessing Key Nutrients and Topical Marvels for Radiant Aging Inside ...
In the realm of healthy aging, a realm where time and science converge, lies a treasure trove of potent key nutrients and topical wonders that can transform the way we approach the aging process. Here we’ll explore the therapeutic properties of L-Baiba, ac-11 cat's claw, 2-HOBA, bergamot, and spermidine - ingested elixirs that nourish our very core while discovering the inherent powers of PTD-DBM, copper tripeptide-1, zinc thymulin, GHK-Cu, Argireline, and Leuphasyl - topical marvels that ado...