METHYLATED B-COMPLEX
High Potency, Comprehensive B-Complex*
- Supports Healthy Methylation & Carbohydrate Metabolism
- Promotes Nervous System, Immune & Adrenal Health
- Supports Neurotransmitter Production For A Positive Mood
- Protects Against Stress-Induced Nutrient Depletion
Active Ingredients: Thiamine (Vitamin B1), Riboflavin (Vitamin B2), Niacin, Vitamin B6, Folate, Vitamin B12, Biotin, Pantothenic Acid, Choline Bitartrate, Inositol
Other Ingredients: Hydroxypropyl Methycellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose)
HOW
Take 1 capsule daily or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
1 Capsule
-
Benefits
- Supports Healthy Methylation & Carbohydrate Metabolism
- Promotes Nervous System, Immune & Adrenal Health
- Supports Neurotransmitter Production For A Positive Mood
- Protects Against Stress-Induced Nutrient Depletion
-
Ingredients
Active Ingredients: Thiamine (Vitamin B1), Riboflavin (Vitamin B2), Niacin, Vitamin B6, Folate, Vitamin B12, Biotin, Pantothenic Acid, Choline Bitartrate, Inositol
Other Ingredients: Hydroxypropyl Methycellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose)
-
How To Use
HOW
Take 1 capsule daily or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
1 Capsule
METHYLATED B-COMPLEX
Formulation
Vitamin B1
- Found In
- Lean Pork Chops, Salmon
- Source
- Thiamine HCl
- Benefits
- Brain, Heart, Immune Function, Eye Health, Metabolism
- Science
- 19,782 published articles
Vitamin B2
- Found In
- Lean Beef, Dairy Products
- Source
- Riboflavin HCl
- Benefits
- Energy Production, Fat, Carb Metabolism
- Science
- 21,401 published articles
Niacin
- Found In
- Red Meat, Poultry, Fish
- Source
- Niacinamide
- Benefits
- Cholesterol, Blood Pressure, Metabolism, Skin Health
- Science
- 14,556
- published articles
Vitamin B6
- Found In
- Avocados, Chick Peas, Spinach, Eggs
- Source
- Pyridoxyl-5-Phosphate
- Benefits
- Brain, Energy, Heart Health
- Science
- 22,042 published articles
Folate
- Found In
- Spinach, Turnips
- Source
- 5-Methyltetrahydrofolic Acid
- Benefits
- Brain, Heart Health, Red Blood Cell Formation
- Science
- 69,828 published articles
Vitamin B12
- Found In
- Organ Meats, Clams
- Source
- Methylcobalamin
- Benefits
- Brain, Mood, Heart, Eye, Red Blood Cell Support
- Science
- 36,493 published articles
Biotin
- Found In
- Egg Yolks, Legumes
- Source
- Vitamin H
- Benefits
- Hair, Skin, Nails and Brain Health
- Science
- 36,292 published articles
Pantothenic Acid (Vitamin B5)
- Found In
- Organ Meats, Beef
- Source
- D-Calcium Pantothenate
- Benefits
- Energy, Metabolism of Fats and Carbs, Cholesterol
- Science
- 4,224 published articles
Choline
- Found In
- Eggs, Liver, Broccol
- Source
- Choline Bitartrate
- Benefits
- Brain Health, Liver Function, Metabolism
- Science
- 87,118 published articles
Inositol
- Found In
- Citrus Fruits, Melons, Beans, Grains, Nuts
- Source
- Myo-Inositol
- Benefits
- Blood Sugar, Cholesterol, Blood Pressure, Ovarian Health
- Science
- 50,145 published articles
High Potency, Balanced Comprehensive B-Complex*
-
METHYLATED B-COMPLEX
This advanced B-complex formulation includes eight essential B vitamins along with choline, inositol, and biologically active folate as 5-MTHF for optimal methylation. Methylation is a critical biochemical process that converts homocysteine into methionine and cysteine, supporting cardiovascular and nervous system health.*
-
OVERVIEW
B vitamins are essential for the body’s ability to convert food into cellular energy. These water-soluble vitamins are absorbed in the small intestine and metabolized in the liver into their active coenzyme forms. Acting as coenzymes in the Krebs cycle, they are vital for the production of adenosine triphosphate (ATP), the body’s primary energy currency. Moreover, B vitamins like folate, B6, and B12 play pivotal roles in methylation, a process crucial for converting homocysteine into methionine and cysteine. Methylation influences DNA repair, gene expression, and overall mental and physical health.*
-
FUNCTIONS OF EACH ESSENTIAL B VITAMIN
Thiamine (Vitamin B1)
Thiamine is a key cofactor in A TP production within the Krebs cycle and is required for metabolizing fats, proteins, and carbohydrates. Modern diets often lack sufficient thiamine due to the over-processing of grains. Research from randomized, double-blind, placebo-controlled trials indicates that high-dose thiamine supplementation may also support balanced blood sugar levels.1*
Riboflavin (Vitamin B2)
Riboflavin serves as a precursor for flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), critical for energy production and antioxidant activity. Riboflavin deficiency can lead to oxidative stress and impaired energy production. Studies suggest that maintaining optimal riboflavin levels can help promote healthy blood pressure, especially in genetically predisposed individuals.2*
Niacin (Vitamin B3)
Niacin, transformed into NAD and NADP in the body, is a cofactor in mitochondrial energy production. It supports oxidation-reduction reactions and promotes cardiovascular health, with substantial evidence demonstrating its role in maintaining healthy cholesterol levels.3*
Vitamin B6
With involvement in over 100 enzymatic reactions, B6 is vital for lipid metabolism, neurotransmitter production, immune function, and hormone regulation. Studies show that higher dietary intake of B6 supports cardiovascular health and enhances lymphocyte activity, promoting immune function in older adults.4,5*
Folate (5-MTHF)
Folate is indispensable for DNA synthesis, methylation, and mitochondrial energy metabolism. Unlike folic acid, which requires enzymatic conversion, 5-MTHF is bioactive and readily utilized by the body. This ensures better folate absorption, particularly in individuals with suboptimal enzyme activity. Folate also supports neural tube development during pregnancy and overall cellular function.*
Vitamin B12
Essential for fat and carbohydrate metabolism, protein synthesis, and mitochondrial energy regulation, B12 is primarily found in animal-based foods. This nutrient supports neurological health, mood, and energy production. V egan and vegetarian diets often lack adequate B12, making supplementation critical.6*
Biotin
Biotin is vital for the metabolism of fats, carbohydrates, and proteins, playing a key role in cellular processes and macromolecule synthesis. It is also associated with promoting healthy hair strength and growth6,7*
Pantothenic Acid (Vitamin B5)
Pantothenic acid and its active form, CoA, are essential for synthesizing fatty acids, phospholipids, amino acids, and steroid hormones. Approximately 95% of CoA resides in mitochondria, underscoring its role in energy production. Research highlights pantothenic acid’s ability to support tissue repair and regulate blood lipids.8,9,10*
Choline Bitartrate
Although not a B vitamin, choline is critical for forming cellular membranes and lipoproteins. It also synthesizes acetylcholine, a neurotransmitter vital for brain and muscle function. Choline supports cognitive health and cellular integrity.* -
REFERENCES
1. Alaei Shahmiri F, Soares MJ, Zhao Y, Sherriff J. Eur J Nutr. 2013 Oct;52(7):1821-4. Epub 2013 May 29.
2. Wilson CP, Ward M, McNulty H, Strain JJ, Trouton TG,Horigan G, Purvis J, Scott JM. Am J Clin Nutr. 2012 Mar;95(3):766-72. Epub 2012 Jan 25.
3. Mason CM, Doneen AL. J Cardiovasc Nurs. 2012 Jul-Aug;27(4):303-16.
4. Rimm EB, Willett WC, Hu FB, et al. JAMA. 1998;279(5):359-364.
5. Meydani SN, Ribaya-Mercado JD, Russell RM, Sahyoun N, Morrow FD, Gershoff SN. Am J Clin Nutr. 1991;53(5):1275-1280.
6. Huskisson E, Maggini S, Ruf M. J Int Med Res. May-Jun 2007;35(3):277-289.
7. Mock DM. Biotin. In: Ziegler E, Filer LJ, eds. Present Knowledge in Nutrition: International Life Sciences Institute; 1996:220-235.
8. Plesofsky-Vig N. Pantothenic Acid. In: Ziegler E, Filer LJ,eds. Present Knowledge in Nutrition: International Life Sciences Institute.; 1996:236-244.
9. Naruta E, Buko V. Exp Toxicol Pathol. 2001 Oct;53(5):393-8.
10. Ellinger S, Stehle P. Curr Opin Clin Nutr Metab Care. 2009 Nov;12(6):588-95. Review.
| Ingredients | Amount Per Serving |
| Vitamin B1 (as Thiamine HCL) | 50 mg |
| Vitamin B2 (as Riboflavin) | 50 mg |
| Niacin (as Niacinamide) | 50 mg |
| Vitamin B6 (as Pyridoxine HCL) | 50 mg |
| Folate (as 5-Methyltetrahydrofolic Acid) | 680 mcg |
| Vitamin B12 (as Methylcobalamin) | 500 mcg |
| Biotin | 75 mcg |
| Pantothenic Acid (as D-Calcium Pantothenate) | 50 mg |
| Choline (as Choline Bitartrate) | 19 mg |
| Inositol | 50 mg |
Other Ingredients: Hydroxypropyl Methycellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose)
Professional Information
People Requiring:
-
Cardiometabolic Protocols
-
Support for Heightened Energy Levels
-
Hormone Support
-
Mood & Neurological Support
-
Sleep & Stress Management
Practitioners Recommend
Methylated B Vitamin Complex: FAQs
Have more questions? We have answers
InfiniCare—your personal concierge for longevity. Our team of experts, including our on-staff physician, are standing by to ensure world-class service.
Call Us 1-888-819-4640
Our team is located in Dallas, TX, USA
-
What is methylation, and why is it important?
Methylation is a natural biochemical process that takes place throughout the body. It contributes to many functions that help maintain normal cellular activity and overall wellness.This process is involved in areas such as:
- Gene activity: Supports normal regulation of how genetic information is expressed
- Cellular maintenance: Supports processes involved in maintaining healthy cells
- Neurotransmitter activity: Supports the body’s production of brain chemicals involved in mood and focus
- Metabolic pathways: Participates in processes related to nutrient metabolism and normal cellular function
- Homocysteine metabolism: Supports the conversion of homocysteine into amino acids such as methionine
-
What is a methylated B-vitamin complex?
A methylated B-complex is a B vitamin supplement that contains active, bioavailable forms of certain vitamins, including methylfolate (L-5-MTHF) and methylcobalamin (vitamin B12). These forms can be used by the body directly rather than requiring additional conversion steps.Methylated B-complex formulas are designed to support normal methylation processes, which are associated with cellular activity, neurotransmitter balance, and energy metabolism. -
What does methylated B-complex do?
A methylated B-complex supports several normal functions involved in everyday wellness, including:- Cellular energy metabolism
- Nervous system function
- Neurotransmitter activity related to mood and focus
- Homocysteine metabolism and cardiovascular wellness
- Immune function and general well-being
- Maintaining adequate intake of essential B vitamins
-
How is InfiniWell’s Methylated B-Complex different from standard B-complex vitamins?
Many traditional B-complex supplements use forms such as folic acid or cyanocobalamin, which the body must convert before they can participate in normal metabolic pathways.InfiniWell’s Methylated B-Complex provides eight essential B vitamins in bioavailable forms, including L-5-MTHF and methylcobalamin. These forms can participate directly in the body’s natural biochemical processes.
The formula also includes additional nutrients that support normal cellular activity:
- L-5-MTHF (methylated folate) and methylcobalamin (B12): Support methylation and homocysteine metabolism
- Vitamin B6 and vitamin B2: Support energy metabolism and normal nervous system activity
- Choline and inositol: Support cell membrane structure and normal neurotransmitter activity
Because the formula uses active coenzyme forms, it may be particularly helpful for individuals whose bodies convert certain B vitamins less efficiently.
If you are unsure whether a methylated B-complex supplement is appropriate for you, consider speaking with a qualified healthcare professional before adding it to your routine. -
Is this supplement good for energy?
B vitamins participate in the body’s energy metabolism. They help convert carbohydrates, fats, and proteins from food into adenosine triphosphate (ATP), the molecule cells use to store and transfer energy.By providing active forms of these nutrients, InfiniWell’s Methylated B-Complex supports normal metabolic processes involved in cellular energy production.
The formula does not rely on stimulants such as caffeine. -
How does this supplement support cognitive wellness?
Studies indicate B vitamins participate in the production and regulation of neurotransmitters such as serotonin, dopamine, and norepinephrine. These brain chemicals are associated with mood, attention, and mental clarity.Maintaining adequate intake of these nutrients supports normal nervous system activity and cognitive wellness. -
How does this supplement support cellular energy and metabolism?
B vitamins function as cofactors for many enzymes involved in energy metabolism. These enzymes participate in pathways that convert nutrients from food into usable cellular energy.The formula includes active coenzyme forms that participate in normal metabolic pathways associated with cellular activity and energy production.
Additional nutrients such as choline and vitamin B5 also support metabolic processes involved in the use of fatty acids and other nutrients. -
Who should consider using a methylated B-complex supplement?
A methylated B-complex supplement may be considered by adults who want additional nutritional support for general wellness.This may include:- Adults experiencing demanding schedules or ongoing stress: Daily stress and lifestyle demands can increase nutritional requirements over time.
- Individuals focused on maintaining consistent energy and mental clarity: B vitamins support pathways associated with energy metabolism and nervous system activity.
- People with genetic variations related to methylation: Certain genetic traits may affect how efficiently the body converts some forms of folate.
- Individuals following vegetarian or vegan diets: Vitamin B12 is primarily found in animal-derived foods, so supplementation may help maintain adequate intake.
-
Is InfiniWell’s Methylated B-Complex safe for daily use?
Yes, when used according to the suggested serving.InfiniWell’s formula is designed for regular use and contains no folic acid or synthetic additives. If you are taking medications, have health concerns, or are considering adding multiple supplements to your routine, it is best to speak with a qualified healthcare professional. -
When should I take Methylated B-Complex?
Take one capsule daily, with or without food.Many people choose to take B vitamins earlier in the day as part of their morning routine. If you are taking additional supplements, a healthcare professional can help you determine the best timing. -
What are the ingredients in Methylated B-Complex?
Active ingredients:- Thiamine (vitamin B1): Supports carbohydrate metabolism and nervous system function
- Riboflavin (vitamin B2): Participates in cellular energy metabolism
- Niacin (vitamin B3): Supports metabolic pathways involved in energy production
- Vitamin B6 (as pyridoxal-5-phosphate): Supports neurotransmitter activity and metabolic processes
- Folate (as L-5-MTHF): Supports methylation and homocysteine metabolism
- Vitamin B12 (as methylcobalamin): Supports nervous system activity and cellular metabolism
- Biotin (vitamin B7): Participates in metabolism of carbohydrates, fats, and proteins
- Pantothenic acid (vitamin B5): Supports energy metabolism and cellular activity
- Choline bitartrate: Supports cell membrane structure and neurotransmitter pathways
- Inositol: Supports cell signaling and normal nervous system activity
- Hydroxypropyl methylcellulose: Plant-based capsule material
- Magnesium stearate: Flow agent used during manufacturing
- Silicon dioxide: For maintaining powder stability
- Vegetable capsule (hypromellose): Cellulose-based capsule shell
-
How does this formula support cardiovascular wellness?
B vitamins such as folate, vitamin B6, and vitamin B12 participate in the body’s homocysteine metabolism pathway. Maintaining normal homocysteine metabolism supports cardiovascular wellness as part of overall nutritional balance. -
How can I get B vitamins through food?
B vitamins are found in a variety of whole foods. Examples include:- Dark leafy vegetables such as spinach and kale
- Whole grains and legumes
- Eggs and dairy products
- Poultry and fish
- Nuts, seeds, and avocados
-
What if I have dietary restrictions?
InfiniWell’s Methylated B-Complex is formulated to fit many dietary lifestyles. The formula contains no dairy, gluten, soy, or artificial colors.Because vitamin B12 is primarily found in animal-derived foods, the supplement may be useful for individuals following vegan or vegetarian diets who want additional support for maintaining adequate B12 intake.
If you have specific dietary concerns, consult a healthcare professional before starting a new supplement. -
Disclaimer
This content is for general informational purposes only and is not medical advice. Always speak with a qualified healthcare professional before starting any new supplement or making changes to your wellness routine.