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DEFEND PRO dietary supplement: 60 capsules for bone, heart & immune support.
Supplement facts panel showing vitamins A, D, E, K2, and herbal extracts per serving.
Clear bottle of dietary supplement capsules; bone, heart, and immune support.
Beige capsules spilling from a clear bottle, next to a glass of water, on a gray surface.
Two dietary supplement bottles, showcasing bone, heart, and immune support benefits, displayed on a kitchen counter.
DEFEND PRO dietary supplement: 60 capsules for bone, heart & immune support.
Supplement facts panel showing vitamins A, D, E, K2, and herbal extracts per serving.
Clear bottle of dietary supplement capsules; bone, heart, and immune support.
Beige capsules spilling from a clear bottle, next to a glass of water, on a gray surface.
Two dietary supplement bottles, showcasing bone, heart, and immune support benefits, displayed on a kitchen counter.

DEFEND PRO

Foundational Combination of Vitamins A, D, & K2*

$49.95
5.0
Rated 5.0 out of 5 stars
718 Reviews
View Ingredients & Nutrition Facts
Qty
  • Supports Healthy Calcium Deposition in Bones & Teeth
  • Promotes Broad Immune System Activation
  • Supports Healthy Levels of Oxidation within Blood Vessels
  • Aids in the Metabolism of Lipids

Active Ingredients: Vitamin A, Vitamin D, Vitamin E, Vitamin K2 MK-7, AstraGin® (Astragalus membranaceus and Panax notoginseng) Root Extracts

Other Ingredients: Nuflow, Vegetable Capsule (Hypromellose)

HOW

Take 1 capsule daily or as directed by your healthcare practitioner.

WHEN

Daily

DOSE

1 Capsule

  • Benefits

    • Supports Healthy Calcium Deposition in Bones & Teeth
    • Promotes Broad Immune System Activation
    • Supports Healthy Levels of Oxidation within Blood Vessels
    • Aids in the Metabolism of Lipids
  • Ingredients

    Active Ingredients: Vitamin A, Vitamin D, Vitamin E, Vitamin K2 MK-7, AstraGin® (Astragalus membranaceus and Panax notoginseng) Root Extracts

    Other Ingredients: Nuflow, Vegetable Capsule (Hypromellose)

  • How To Use

    HOW

    Take 1 capsule daily or as directed by your healthcare practitioner.

    WHEN

    Daily

    DOSE

    1 Capsule

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DEFEND PRO

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  • One-Time $49.95

Formulation

Vitamin A

  • Found In
  • Sweet Potato, Carrot, Spinach, Liver, Mango, Eggs
  • Source
  • Retinyl Palmitate
  • Benefits
  • Eye Health, Immune Function, Skin
  • Science
  • 59,527 published articles

Vitamin D

  • Found In
  • Sunlight, Egg Yolks, Mushrooms, Salmon
  • Source
  • Cholecalciferol
  • Benefits
  • Bone Formation, Heart Health, Immune Function
  • Science
  • 130,124 published articles

Vitamin E

  • Found In
  • Seeds, Avocados, Almonds
  • Source
  • d-alpha tocopherol succinate
  • Benefits
  • Heart, Brain, Bone Health, Antioxidant Support
  • Science
  • 47,608 published articles

Vitamin K2

  • Found In
  • Natto, Soy, Fermented Foods, Grass-Fed Butter 
  • Source 
  • K2VITAL DELTA All-Trans Menaquinone-7 
  • Benefits 
  • Heart Heatlh, Hormones, Brain Function 
  • Science 
  • 5,192 published articles

AstraGin®

  • Found In
  • Astragalus and Notoginseng
  • Source
  • Astragalus membranaceus and Panax Notoginseng
  • Benefits
  • Nutrient Absorption, Gut Health
  • Science
  • 2,186 published articles
overview

Foundational Combination of Vitamins A, D, and K2*

  • OVERVIEW

    Vitamins A, D, and K2 are essential nutrients that play important roles in various biological processes. Vitamin A is vital for vision, immune function, and cellular growth and differentiation. Vitamin D is essential for bone health, and immune function, and has been linked to numerous other health benefits. Vitamin K2 is necessary to support bone health and cardiovascular health. Since these three nutrients work together and depend on one another, their combination in a dietary supplement is key. AstraGin®, a proprietary blend of Astragalus membranaceus and Panax notoginseng extracts, serves to improve nutrient absorption and enhance the bioavailability of certain compounds, these vitamins included. When combined these nutrients and AstraGin® can create a synergistic effect, potentially enhancing their benefits and improving overall health.


    Vitamins A, D, and K2 are fat-soluble vitamins that play essential roles in various physiological processes, and they are interrelated in several ways. While they have distinct roles in the body, these vitamins depend on each other to some extent.


    One example of their interdependence is their relationship with bone health. Vitamin D helps to regulate calcium and phosphorus levels in the body, which are necessary for bone mineralization. Vitamin K2 activates proteins that help to transport calcium into bones, while vitamin A helps to regulate bone cell activity. Together, these vitamins work synergistically to support bone health. Another example is their role in immune function. Vitamin A is essential for the development and maintenance of immune cells, while vitamin D helps to regulate the immune response. Vitamin K2 also supports immune function by activating proteins that help to fight infection.

  • BONE HEALTH

    The interrelationship between vitamins A, D, and K2 is especially significant in bone health.Vitamin D supports calcium and phosphorus absorption, both essential for bone mineralization.Vitamin K2 activates proteins that facilitate calcium transport into bone tissue, and vitamin A helps regulate bone cell activity. Together, these nutrients may work to maintain healthy bone structure and function.

  • HEART HEALTH

    Vitamins A, D, and K2 are associated with heart health in several ways. Vitamin A is involved inlipid metabolism, which supports cell membrane integrity and cardiovascular function. Researchindicates that it may help regulate oxidative stress and promote arterial health.1 Vitamin D is known to support endothelial function, contributing to vascular health. Vitamin K2 has been studied for its role in activating proteins involved in arterial health, particularly in conjunction with vitamin D. For example, research on postmenopausal women has suggested that combined supplementation with vitamins K2 and D may promote arterial flexibility.2

  • IMMUNE HEALTH

    Vitamins A and D are vital for immune system function. Vitamin A supports the maintenance of healthy epithelial tissues, the body’s first line of defense against pathogens. Vitamin D has immunomodulatory effects, including supporting the activity of T and B cells.3 Studies have linked vitamin D to the regulation of immune cell activity, cytokine production, and antimicrobial peptide expression.4 Vitamin K2 also plays a role in immune function through the activation of proteins that support immune responses, such as osteocalcin, which has been shown to influence immune cell activity.

  • SEX HORMONE METABOLISM

    Both vitamins A and D are involved in pathways related to hormone regulation. Retinoic acid, derived from vitamin A, supports the enzymatic activity required for synthesizing hormones like testosterone and estradiol. Vitamin D interacts with the hypothalamus and pituitary gland to regulate hormone production, which has implications for maintaining balanced sex hormone levels.

  • NUTRIENT ABSORPTION

    AstraGin® has been investigated for its potential to enhance the absorption of nutrients by increasing the activity of transport proteins, such as GLUT4. These effects may improve the bioavailability of vitamins, including K2 and other nutrients. AstraGin® also contains compounds studied for their antioxidant properties and their ability to support vascular health, although further research is needed to establish these effects in clinical settings.

  • REFERENCES

    1. Zalaket J, Hanna-Wakim L, Matta J. Cholesterol. 2018 Jun 3;2018:8050512. doi: 10.1155/2018/8050512. PMID:29971161;PMCID: PMC6008699.

    2. Maresz K.. Integr Med (Encinitas). 2015 Feb;14(1):34-9.

    3. Dupuis, M.L., Pagano, M.T., Pierdominici, M. et al. Biol Sex Differ 12, 12 (2021).

    4. Martens PJ, Gysemans C, Verstuyf A, Mathieu AC. Nutrients. 2020 Apr 28;12(5):1248.

Nutrition
Serving Size: 1 Capsule | Servings Per Container: 60
IngredientsAmount Per Serving
Vitamin A (as retinyl palmitate) (5,000 IU) 
1515 mcg
Vitamin D (as Vitamin D3, cholecalciferol) (5,000 IU)
250 mcg
Vitamin E (as d-alpha tocopherol succinate) (121 IU)
100 mg
Vitamin K2 MK-7 (as K2VITAL® DELTA All-Trans Menaquinone-7)
300 mcg
AstraGin® (Astragalus membranaceus and Panax notoginseng) Root Extracts50 mg

Other Ingredients: Nuflow, Vegetable Capsule (Hypromellose, Titanium Dioxide)

Practitioner Resources

Professional Information

People Requiring:

  • Cardiometabolic Support

  • Bone Building & Strengthening Aid

  • Immune System Support

  • Sex Hormone Metabolism Support

Your Peers Approve. See Why

5.0
Rated 5.0 out of 5 stars
Based on 718 reviews
Total 5 star reviews: 686 Total 4 star reviews: 30 Total 3 star reviews: 2 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend these products
Reviews Summary
Customers say these supplements are effective and easy to use. Many reviews mention fast shipping and quick delivery times. The website is frequently described as easy to navigate and user-friendly, with straightforward ordering processes. Common feedback includes praise for product quality and consistency. Users report positive experiences with customer service, noting quick responses to questions and professional support. Several customers mention using subscription services and becoming repeat purchasers. While some note the products are not the cheapest option, many feel they provide good value. The company is often described as reliable and trustworthy.
718 reviews
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    Only been a customer for less than a month. So far it’s great and it alerts me when my next subrcripbion is up so I can adjust.

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    Your website is great and your customer service has been very responsive.

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    Great customer service with speedy delivery.

    Awesome results and fast shipping. I ordered BPC-Lx™ Pro because Dr. Ashley Froese’s podcast convinced me that a solid oral spray can actually work as well as injections for recovery. I was surprised at how fast it arrived, showed up at my door in just a couple of days.

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Defend Pro, Immune Support Supplement: FAQs

InfiniWell Defend Pro is a foundational immune support supplement designed to support overall health and wellness. It combines vitamins A, D, K2, and E with AstraGin®, a patented blend of Astragalus membranaceus and Panax notoginseng extracts that has been studied for its role in supporting nutrient absorption.

Together, these bioactive compounds help support immune system function, calcium metabolism related to bone health, lipid metabolism, and healthy blood vessel integrity. This once-daily formula is free of stimulants and hormones, making it suitable for long-term use.

Have more questions? We have answers

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Go to Live Chat Call Us 1-888-819-4640

Our team is located in Dallas, TX, USA

  • What are immune health supplements?

    Immune health supplements are dietary products that provide vitamins, minerals, and other nutrients needed for normal immune function. They’re intended to help maintain a healthy immune response, particularly when diet may not supply enough of these nutrients.

    Common examples include:

    • Vitamin C supplements: Often sourced from citrus fruits or plant foods, vitamin C supports immune cell function and antioxidant activity.
    • Vitamin D supplements: These are especially useful for people who get little sun, since adequate vitamin D supports normal immune function.
    • Zinc and selenium supplements: Zinc and selenium are essential minerals that support normal immune function and antioxidant activity.
    • Probiotics: These support gut health, which promotes immune system balance.
    • Vitamin A, E, and K2: These are fat-soluble vitamins that support immune system function, provide antioxidant activity, and help maintain overall health. 
    While immune support supplements can help fill nutrient gaps, they work best when paired with healthy eating, adequate sleep, regular activity, and stress management. For personalized advice, especially if you’re considering combining multiple supplements, consult a healthcare professional.

  • What is InfiniWell Defend Pro?

    Defend Pro is an immune health supplement that combines fat-soluble vitamins with AstraGin® to support nutrient uptake. The formula is designed to support normal immune function, help maintain bone and cardiovascular health, and promote healthy lipid metabolism.

    Unlike single-nutrient vitamin C supplements or vitamin D-only products, Defend Pro delivers a complementary blend that supports immune function, blood vessel health, and calcium balance in one capsule.

  • How does Defend Pro support the immune system?

    Defend Pro works by providing vitamins and compounds that play a role in healthy immune function:

    • Vitamin A: Supports the body’s natural barriers and helps maintain healthy immune cell activity.
    • Vitamin D: Supports normal immune function. Adequate levels are important for maintaining overall immune balance.
    • Vitamin E: Acts as an antioxidant, helping support healthy cell function and immune cell activity.
    • Vitamin K2 (MK-7): Best known for supporting calcium metabolism, K2 also helps maintain blood vessel health, which supports overall wellness.
    • AstraGin: A patented plant extract that supports nutrient absorption, helping the body make better use of amino acids, vitamins, and minerals. 
    Maintaining adequate levels of these vitamins helps support normal immune function.

  • Who should take this immune support supplement?

    Defend Pro is designed for healthy adults who want to support immune function, bone strength, and overall wellness.

    Healthy adults may choose daily immune support supplements to help maintain consistent intake of essential vitamins that support normal immune function. Older adults and those with limited sun exposure may benefit from supplemental support to help maintain healthy nutrient levels.

    It can also be a good option for individuals who want broader nutrient coverage than vitamin C alone, since it combines fat-soluble vitamins that complement vitamin C and other immune support nutrients.

    Always check with a healthcare professional before starting any new supplement, especially if you’re taking medications.

  • How does Defend Pro compare to vitamin C supplements?

    Vitamin C is a well-known immune support nutrient, naturally present in citrus fruits, red and green peppers, and many plant foods. It supports immune cell function, provides antioxidant support, and is widely used in the immune health supplement category.

    Defend Pro is built around fat-soluble vitamins (A, D, E, and K2) that offer additional support for immune function and overall health.

    When combined with vitamin C from food or oral supplements, Defend Pro provides broader nutrient coverage. The blend complements vitamin C by providing fat-soluble vitamins that support antioxidant activity, cellular health, and immune function.

  • What are the benefits of taking Defend Pro daily?

    Regular use of Defend Pro may support:

    • Immune balance: Provides nutrients that help maintain normal immune function as part of everyday wellness.
    • Healthy bones and teeth: Supports calcium metabolism for structural health.
    • Cardiovascular support: Helps maintain healthy blood vessels as part of overall wellness.
    • Lipid metabolism: Supports how the body processes and manages fats.
    • Overall health: Provides essential nutrients that support many systems beyond immune function.

  • When should I take Defend Pro?

    Take 1 capsule daily with water, preferably alongside a meal that contains healthy fats (such as fatty fish, olive oil, or nuts) to support absorption of fat-soluble vitamins. Consistency is key. Daily use supports steady nutrient levels for immune function and overall health.

  • Can Defend Pro be taken with other immune health supplements?

    Yes. Defend Pro is often combined with:

    • Vitamin C supplements: These provide additional immune and antioxidant support.
    • Mineral supplements (such as zinc or selenium): These essential minerals support normal immune function and antioxidant activity.
    • Probiotics and related supplements: Gut health supplements support digestive balance, which supports immune function and nutrient absorption, allowing the body to make better use of vitamins and minerals. 
    For best results, avoid taking large amounts of overlapping nutrients unless advised by a healthcare professional. This helps you stay within safe intake levels.

  • Is Defend Pro safe for long-term use?

    Yes. Defend Pro is formulated with nutrients at safe daily levels and contains no stimulants or synthetic hormones. Always follow the recommended serving size, and talk with a healthcare professional before exceeding recommended use.

  • How can I keep my immune system healthy every day?

    Maintaining a healthy immune system goes beyond taking oral supplements. A combination of healthy eating, regular movement, adequate sleep, and stress management helps maintain normal immune function.

    Nutrients play an important role here, and certain vitamins and minerals—like vitamin A, vitamin D, vitamin E, selenium, and zinc—are often emphasized for daily immune support.

  • What foods can support immune health alongside supplements?

    Balanced nutrition is a cornerstone of immune system function. Eating green leafy vegetables, citrus fruits, wheat germ, fermented foods, and foods rich in beta-carotene provides essential vitamins and minerals.

    These nutrient-dense foods help you stay healthy and work together with dietary supplements to promote immune system function.

  • Disclaimer

    This content is for general informational purposes only and is not medical advice. Always talk to a qualified healthcare professional before starting any new supplement or making changes to your wellness routine.