GI PRIME
Comprehensive Pre/Pro/Post Biotic Formula*
- Supports a Healthy Gut Microbiota
- Strengthens Immune System
- Aids in Optimizing Gut Barrier Integrity
- Modulates Immune Response in the Gut via Activation of pDC’s
- Supports Digestive Function & Regularity
Active Ingredients: Dried Yeast Fermentate (EpiCor®) (Saccharomyces cerevisiae), Lactococcus lactis strain Plasma (IMMUSE™ Paraprobiotic), ButyraGen™, Spore Probiotic Blend - Bacillus Coagulans (SNZ 1969), Bacillus Subtillus (SNZ 1972), Bacillus Clausii (SNZ 1971)
Other Ingredients: Vegetable Capsule (Hypromellose), Rice Powder, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide.
HOW
Take 3 capsules daily or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
3 Capsules
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Benefits
- Supports a Healthy Gut Microbiota
- Strengthens Immune System
- Aids in Optimizing Gut Barrier Integrity
- Modulates Immune Response in the Gut via Activation of pDC’s
- Supports Digestive Function & Regularity
-
Ingredients
Active Ingredients: Dried Yeast Fermentate (EpiCor®) (Saccharomyces cerevisiae), Lactococcus lactis strain Plasma (IMMUSE™ Paraprobiotic), ButyraGen™, Spore Probiotic Blend - Bacillus Coagulans (SNZ 1969), Bacillus Subtillus (SNZ 1972), Bacillus Clausii (SNZ 1971)
Other Ingredients: Vegetable Capsule (Hypromellose), Rice Powder, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide.
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How To Use
HOW
Take 3 capsules daily or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
3 Capsules
Formulation
EpiCor®
- Found In
- Brewer's Yeast
- Source
- Saccharomyces cerevisiae
- Benefits
- Immune Support, Digestion
- Science
- 97 published articles
IMMUSE™ (LC-Plasma)
- Found In
- Probiotic Bacteria
- Source
- Lactobacillus lactis Plasma
- Benefits
- Immune Support, Digestion
- Science
- 2,969 published articles
ButyraGen™
- Found In
- Butter
- Source
- Tributyrin
- Benefits
- Digestion, Brain Support
- Science
- 871 published articles
Spore Probiotics
- Found In
- Plant and Soil Based
- Source
- Bacillus coagulans, Bacillus subtilis, Bacillus clausii
- Benefits
- Digestion, Brain Support
- Science
- 853 published articles
Comprehensive Pre/Pro/Post Biotic Formula*
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OVERVIEW
GI Prime is a dietary supplement formulated to support gut health and promote overall digestive well-being. This advanced blend combines the following ingredients known for their beneficial effects on gut microbiota and immune function: Epicor® , which has been shown to support gut health by promoting a balanced gut microbiota, modulating immune function, and optimizing gut barrier integrity. IMMUSETM , a cutting-edge postbiotic, has been clinically shown to aid the body's natural defenses at the cellular level to provide comprehensive gut and immune support year-round. ButyragenTM serves as a prebiotic, butyrate-producing innovation. All of these well researched, branded ingredients are combined with a 12 billion CFU blend of Bacillus coagulans, subtilis, and clausii.
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INGREDIENTS
EpiCor®
EpiCor® is a postbiotic, a term which when broken down means ‘after’ and ‘life’. The term postbiotic appropriately refers to substances derived after the microorganisms are no longer alive, or, in other words, inanimate, dead or inactivated but still confer a health benefit. EpiCor® is a whole food fermentate made using yeast (“Saccharomyces cerevisiae”) that goes through a closely held trade secret fermentation and drying processes. This fermentation process makes a unique fingerprint of metabolites including proteins, polyphenols, vitamins, minerals, amino acids, polysaccharides, fiber, and other nutrients.
Over a dozen published studies show EpiCor® postbiotic helps to support your immune system and modulate the gut microbiota. The direct role it has on gut health relies on two main mechanisms of action. First, the modulation of gut microbiota: Epicor® promotes a balanced gut microbiota by supporting the growth of beneficial bacteria, such as Lactobacillus and Bifidobacterium species, while inhibiting the growth of potentially harmful bacteria. This modulation helps maintain a healthy microbial balance, which is essential for optimal digestion, nutrient absorption, and overall gut health. Second, is through supporting gut barrier integrity: Epicor® supports the integrity and function of the gut barrier, which acts as the primary protective barrier between the gut lumen (the inner space of the intestines) and the rest of the body. It prevents the translocation of harmful substances, such as toxins and bacteria, into the bloodstream. By strengthening the gut barrier, Epicor® aids in ensuring minimal amount of gut permeability and helps maintain an overall healthy gut ecosystem.1,2IMMUSETM
IMMUSETM is a novel postbiotic, specifically targeting the immune system. The primary benefit of IMMUSETM (Lactococcus lactis JCM 5805) is its ability to promote pDC, which are a rare subset of immune cells that have been described as the commander-in-chief or leader of the immune system. It's been well established that pDC’s themselves activate natural killer cells, killer T cells, helper T cells and B cells. In short, this postbiotic provides comprehensive immune support and is backed by 30 published studies, 15 of which are human trials.3,4 In addition to IMMUSETM's clinical successes, it’s been awarded the Product of the Y ear by NutraIngredients-Asia, as well as being bestowed the North American Immune Health Ingredient New Product Innovation Award. Both of these honors further validate the strength of this ingredient as a groundbreaking postbiotic.
ButyraGenTMButyraGenTM is an innovative next-generation prebiotic – its primary function is as a direct butyrate generator that lends to gut health and beyond, generating high levels of butyrate directly in the colon. This is what sets it apart from traditional prebiotics: its unique ability to generate butyrate mostly independent of the state of the microbiome. In other words, the microbiome doesn’t have to be fully balanced and in its most optimal state in order for butyrate to be made.
Other prebiotics work solely by feeding bacteria that then generate butyrate and are completely dependent on the state of the microbiome. ButyraGenTM, which only requires 200 mg, can be especially effective when combined with probiotics to further promote the health benefits of the probiotic strains. When consumed, ButyraGenTM is broken down into butyrate, which serves as a primary energy source for the cells lining the intestinal tract. Butyrate supports the integrity of the gut barrier. This helps prevent the translocation of harmful substances and toxins, maintaining gut health and optimal digestion.5,6
Additionally, butyrate aids in optimizing digestion and nutrient absorption. But the impact is not limited to the digestive system alone. The gut-brain axis is influenced by butyrate production in the gut as well. Butyrate acts as a signaling molecule, communicating with the central nervous system and influencing brain function. By supporting butyrate production, ButyraGenTM indirectly contributes to a balanced gut-brain axis, potentially impacting cognitive function, mood, and mental well-being.
Bacillus Strains of ProbioticsThe probiotic strains Bacillus coagulans, Bacillus subtilis, and Bacillus clausii, found in GI Prime, can potentially influence the gut-brain axis. The gut-brain axis refers to the bidirectional communication pathway between the gut and the brain, involving the nervous, endocrine, and immune systems.
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REFERENCES
1. Pinheiro, I., et al. . BMC Complement Altern Med 2017, 17 (1), 441.
2. Ducray, H.A.G., et al. J Appl Microbiol 2019, 127, 1192—1206.
3. Sugimura T, Takahashi H, Jounai K, Ohshio K, Kanayama M, Tazumi K, Tanihata Y , Miura Y , Fujiwara D, Y amamoto N. (2015) Br J Nutr. 3:1-7.
4. Suzuki H, Ohshio K, Fujiwara D. (2016) Biosci Biotec Biochem. 80: 798-800.
5. Rios-Covian D, Ruas-Madiedo P , Margolles A, Gueimonde M, de los Reyes-Gavilan CG, Salazar N. Front Microbiol 2016;7:9.
6. Gao ZG, Yin J, Zhang J, Ward RE, Martin RJ, Lefevre M, Cefalu WT, Y e JP . Diabetes 2009;58:1509–17.
| Ingredients | Amount Per Serving |
| Dried Yeast Fermentate (EpiCor®) (Saccharomyces cerevisiae) | 500 mg |
| Lactococcus lactis strain Plasma (IMMUSE™ Paraprobiotic) | 50 mg |
| ButyraGen™ | 200 mg |
| Spore Probiotic Blend Bacillus Coagulans (SNZ 1969) Bacillus Subtillus (SNZ 1972) Bacillus Clausii (SNZ 1971) | 12 billion CFU |
Other Ingredients: Vegetable Capsule (Hypromellose), Rice Powder, Microcrystalline Cellulose, Magnesium Searate, Silicon Dioxide.
Professional Information
People Requiring:
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Overall Digestive Support
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Acute & Ongoing Immune System Support
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Gut Dysbiosis Assistance
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Gut Permeability Protocols
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FAQs
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Why is maintaining a healthy gut so important?
Your gut impacts nearly every part of your body—from your digestive tract to your mental health. The gut, also known as the GI tract, is home to trillions of good bacteria that keep your digestive system running smoothly.Here’s why a healthy gut matters:
- Regular digestion and nutrient absorption: Both are essential for sustained energy and a strong immune system.
- Beneficial bacteria balance: Eating fiber-rich foods helps these microbes thrive, supporting a strong, resilient gut lining.
- Blood sugar regulation and nervous system function: Both contribute to steady energy levels and balanced mood.
- Lower risk of health issues: An imbalanced gut microbiome has been linked to high blood pressure and digestive discomfort.
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How does a healthy gut impact mental health?
A healthy gut influences the gut-brain axis—a complex communication system linking the digestive system and the brain. A diverse and balanced gut microbiome helps produce neurotransmitters that affect mood, stress response, and sleep patterns.Here’s how a healthy gut can support mental health:
- Neurotransmitter production: A balanced gut microbiome produces neurotransmitters that influence mood and stress response. Studies suggest that supporting gut-brain communication pathways—including neurotransmitter synthesis, immune signaling, and metabolic processes—may contribute to better gut health and a more positive mental outlook.
- Immune system strength: Poor lifestyle habits, lack of high-fiber foods, or insufficient digestive supplementation can disrupt gut balance, weakening the body's defenses. By helping absorb nutrients and restore balance, a healthy gut helps the body respond more effectively to stress.
- Nutrient absorption: A well-functioning gut ensures nutrients are properly absorbed. Good gut health also improves digestion overall, helping sustain mood and energy.
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What is InfiniWell’s GI Prime supplement?
GI Prime by InfiniWell is a dietary supplement designed to support gut health using a carefully formulated blend of bioactive ingredients.Each serving contains a combination of dried yeast fermentate (EpiCor), IMMUSE™ paraprobiotic, ButyraGen™, and a spore probiotic blend. These ingredients work synergistically to nourish the gut microbiome, support immune function, and promote digestive comfort.
GI Prime works best when paired with a balanced diet and a healthy lifestyle, which together promote gut health and overall well-being. -
What are the benefits of the GI Prime supplement?
By supporting a healthy gut microbiome and immune system, InfiniWell’s GI Prime supplement offers a range of potential benefits:- Gut microbiota balance: GI Prime supports a healthy gut microbiome by nourishing beneficial bacteria and encouraging gut ecosystem diversity.
- Immune system support: By modulating the activity of immune cells in the gut—specifically plasmacytoid dendritic cells (pDCs)—GI Prime may help strengthen immune system defenses against occasional digestive discomfort and other stressors.
- Gut barrier integrity: A healthy gut barrier supports nutrient absorption and helps maintain overall gut health. GI Prime’s ingredients, including ButyraGen, may help maintain the integrity of the gut lining, supporting digestive comfort and reducing the risk of occasional stomach discomfort.
- Digestive function and regularity: By promoting gut microbiome balance and supporting digestive enzymes, GI Prime helps maintain healthy digestion and encourages regular bowel movements.
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What are the active ingredients in GI Prime?
GI Prime contains a carefully selected blend of ingredients designed to support digestive health, immune function, and overall gut balance:- Dried yeast fermentate (EpiCor): A postbiotic derived from fermented saccharomyces cerevisiae that supports immune health and gut microbiota balance.
- Lactococcus lactis strain plasma (IMMUSE paraprobiotic): A clinically studied postbiotic that may support immune health by activating plasmacytoid dendritic cells, which help coordinate the body's immune responses.
- ButyraGen: A prebiotic that supports butyrate production in the gut, which is essential for promoting gut lining integrity and digestive health.
- Spore probiotic blend: Includes Bacillus coagulans (SNZ 1969), Bacillus subtilis (SNZ 1972), and Bacillus clausii (SNZ 1971)—spore-forming probiotics that support gut balance and healthy digestion.
- Vegetable capsule (hypromellose): A plant-derived capsule shell that makes the supplement easy to swallow
- Rice powder: Helps distribute ingredients evenly inside the capsule
- Microcrystalline cellulose: A natural filler that adds bulk to the capsule and keeps the ingredients stable
- Magnesium stearate: A plant-based lubricant that prevents clumping during manufacturing
- Silicon dioxide: An anti-caking agent that keeps the powder free-flowing
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What makes GI Prime different from other gut health supplements?
Unlike many probiotic supplements, GI Prime uses a combination of postbiotics, paraprobiotics, prebiotics, and spore-based probiotics to support gut health in different ways:- Postbiotics: Beneficial compounds produced during the fermentation of dietary fibers and plant-based materials by gut bacteria.
- Paraprobiotics: Inactive bacterial components that help modulate immune responses and reinforce gut defenses.
- Prebiotics: Nutrients that feed friendly gut bacteria, promoting their growth and activity.
- Spore-based probiotics: Robust probiotic strains that survive stomach acid, ensuring they reach the intestines alive.
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How does GI Prime support the gut microbiome and immune system?
GI Prime supports the gut microbiome by nourishing beneficial bacteria and providing substrates (like ButyraGen) that promote the production of short-chain fatty acids, including butyrate, which are essential for gut lining health.The immune system benefits from the presence of IMMUSE paraprobiotic, which helps activate plasmacytoid dendritic cells in the gut—important players in immune defense. This combination of microbiome and immune support helps maintain a strong gut-immune connection. -
Can GI Prime support digestive comfort and regularity?
Yes. By supporting a healthy gut microbiota and digestive enzyme production, GI Prime may contribute to healthy digestion and regularity. This can be helpful for maintaining digestive comfort and may assist with occasional stomach pain, digestive discomfort, and bloating that are sometimes associated with an imbalanced gut microbiome.Disclaimer: GI Prime is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Check with your healthcare provider before using this product, particularly if you have any health conditions or are taking other medications. -
How do I take GI Prime?
For best results, take GI Prime daily. Swallow 3 capsules with water, preferably with a meal for optimal absorption, or as directed by your healthcare professional.Supplements for a healthy gut are often recommended by experts to complement whole grains, smart food choices, and a balanced diet—all important for maintaining gut balance. -
Is GI Prime suitable for women’s health and whole-body wellness?
Absolutely. A balanced gut microbiome is linked to overall health, including women’s health concerns like regular digestion, immune resilience, and mood balance. -
Are there any side effects?
InfiniWell’s GI Prime is generally well-tolerated and made from high-quality, strictly regulated ingredients. As with any new supplement, consult your healthcare provider before use, especially if you have medical conditions, are taking medication, or experience ongoing digestive discomfort. -
What should I look for in a quality gut health supplement?
When choosing healthy gut supplements, consider the following key factors:- Clear ingredient listing: Look for transparency and recognizable names like EpiCor, IMMUSE, and ButyraGen. Many of these ingredients are found naturally in fermented foods and are included in some of the best supplements for healthy gut support.
- GMP-compliant manufacturing: InfiniWell adheres to Good Manufacturing Practices for safety and quality, so you know you’re getting a supplement that meets strict standards.
- No artificial additives: GI Prime is free from synthetic colors, preservatives, and sweeteners.
- Scientific support: The ingredients in GI Prime are backed by research and known for their potential health benefits.
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Glossary
Terms to know:- Beneficial bacteria: Friendly microbes that aid digestion and support overall health.
- Gut barrier: The protective lining of the gut that supports nutrient absorption and immune function.
- Gut microbiota: The community of bacteria in the gut, important for digestion and immune health.
- Healthy microbiome: A balanced community of gut microbes that promotes digestion, immune health, and overall wellness.
- Live bacteria vs. friendly bacteria: Live bacteria are active, viable microorganisms that can colonize the gut. Friendly bacteria is a broader term that includes both live and beneficial microbes that support gut health.
- pDCs (plasmacytoid dendritic cells): Key immune cells in the gut that help coordinate immune system responses.
- Postbiotic: Beneficial byproducts of fermentation that support gut health and may help regulate immune responses.
- Prebiotic: Substances that feed beneficial gut bacteria, helping them thrive and produce short-chain fatty acids and amino acids that support digestion and gut lining integrity.
- Prebiotic fiber: A type of fiber found naturally in whole grains, fruits, and vegetables that feeds friendly gut bacteria.
- Prebiotic supplements: Dietary supplements containing prebiotic fibers that feed and nourish beneficial gut bacteria.
- Probiotic: Live microorganisms that promote a balanced gut microbiome and support digestive health. Taking probiotics—through supplements or fermented foods—can help maintain gut health and may improve digestive comfort.