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Cardio Prime+ Cardiovascular Support dietary supplement: 60 capsules.
CARDIO PRIME+
Clear bottle of cardiovascular support dietary supplement capsules; 60 capsules total.
Cardiovascular support supplement capsules in a clear bottle, spilled on a white surface.
Cardio Prime+ Cardiovascular Support dietary supplement: 60 capsules.
CARDIO PRIME+
Clear bottle of cardiovascular support dietary supplement capsules; 60 capsules total.
Cardiovascular support supplement capsules in a clear bottle, spilled on a white surface.

CARDIO PRIME+

Advanced Cardiometabolic Support*

$79.95
4.9
Rated 4.9 out of 5 stars
752 Reviews
View Ingredients & Nutrition Facts
Qty
  • Supports Vessel Health & Pliability
  • Aids in Blood Pressure Regulation
  • Supports Fibrinolytic Activity
  • Maintains Already Healthy Cholesterol Levels
  • Promotes Healthy Blood Sugar & Insulin Metabolism

Active Ingredients: Niacin, Copper, NAD3® Proprietary Blend (Wasabi Extract, Theacrine, Cuprous Niacin), VasoDrive AP®, Citrus Bergamot Extract, CurcuPrime® Tetrahydrocurcumin, NSK-SD® Nattokinase

Other Ingredients: Microcrystalline Cellulose, Magnesium Stearate (Vegetable), Silica, Vegetable Capsule (Hypromellose). Contains soy and milk.

HOW

Take 2 capsules daily with water or as directed by your healthcare practitioner.

WHEN

Daily

DOSE

2 Capsules

  • Benefits

    • Supports Vessel Health & Pliability
    • Aids in Blood Pressure Regulation
    • Supports Fibrinolytic Activity
    • Maintains Already Healthy Cholesterol Levels
    • Promotes Healthy Blood Sugar & Insulin Metabolism
  • Ingredients

    Active Ingredients: Niacin, Copper, NAD3® Proprietary Blend (Wasabi Extract, Theacrine, Cuprous Niacin), VasoDrive AP®, Citrus Bergamot Extract, CurcuPrime® Tetrahydrocurcumin, NSK-SD® Nattokinase

    Other Ingredients: Microcrystalline Cellulose, Magnesium Stearate (Vegetable), Silica, Vegetable Capsule (Hypromellose). Contains soy and milk.

  • How To Use

    HOW

    Take 2 capsules daily with water or as directed by your healthcare practitioner.

    WHEN

    Daily

    DOSE

    2 Capsules

or set up interest-free payments with Shop Pay Delivery every 30 Days. Cancel anytime.

CARDIO PRIME+

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Formulation

Niacin

  • Found In
  • Red Meat, Poultry, Fish, Brown Rice 
  • Source 
  • Niacinamide 
  • Benefits 
  • Cholesterol, Blood Pressure, Metabolism, Skin Health 
  • Science 
  • 14,556 published articles

NAD3® Proprietary Blend

  • Found In
  • Wasabi, Tea 
  • Source 
  • Wasabia japonica, Theacrine, Cuprous Niacin 
  • Benefits 
  • Energy, Heart, Brain Health 
  • Science 
  • 52 published articles

Citrus Bergamot Extract

  • Found In
  • Bergamot Fruit (Citrus bergamia) 
  • Source 
  • Bergamonte 
  • Benefits 
  • Cholesterol, Immune System, Mood, Mental Alertness 
  • Science 
  • 471 published articles

Curcumin

  • Found In
  • Turmeric 
  • Source 
  • TurmiPure Gold®, CurcuPrime® Tetrahydrocurcumin 
  • Benefits 
  • Brain, Immune, Metabolism, Gut Health 
  • Science 
  • 22,552 published articles

VasoDrive AP®

  • Found In
  • Dairy Products
  • Source
  • (Isoleucyl-prolyl-proline and Valyl-prolyl-proline)
  • Benefits
  • Blood Pressure, Heart Health, Libido
  • Science
  • 44 published articles

NSK-SD® Nattokinase

  • Found In
  • Synthesized from Natto via Fermentation Process 
  • Source 
  • Nattokinase Enzyme 
  • Benefits 
  • Blood Pressure, Heart Health 
  • Science 
  • 246 published articles
overview

Overview

  • OVERVIEW

    Cardiovascular and metabolic health are multi-faceted systems that require a holistic approach to provide authentic, effective support. More often than not, two overlooked areas are (1) energy production and (2) glucose metabolism. The connection between heart health and these two additional factors is very well established and the data continues confirming as much. So with these essential elements layered on top of more ‘tried and true’ ingredients that research has long supported as being vital to cardiovascular health, InfiniWell carefully and meticulously put together this ‘all-in-one’, evidence-based cardiometabolic formula, called Cardio Prime+. Cardio Prime+ represents the latest nutritional innovation to provide a multi-faceted approach to cardiometabolic health.

  • INGREDIENTS

    NAD3®


    The first, and perhaps most cutting-edge inclusion, is the NAD3® . This is a multi patents-pending nutraceutical containing a unique Wasabi japonica extract, Theacrine, and Copper(I)-Niacin complex. Preliminary pre-clinical and human studies, in collaboration with the DNA methylation and epigenetic experts at TruDiagnostic and the multi-omics Molecular and Applied Sciences Laboratory at Auburn University, suggest the mechanism by which this trio works is by supporting enzymes that facilitate the conversion of NAD+ precursors, such as Niacin, Niacinamide, Nicotinamide Riboside (NR) and/or NMN to NAD+, while also regulating the overactivity of proteins that deplete & consume NAD+. Collectively, these data support the use of NAD3® in combination with any NAD+ precursor for facilitating net cellular NAD+ status.


    NSK-SD® Nattokinase


    NSK-SD® Nattokinase - The second ingredient is a proteolytic enzyme, which operates very differently from a digestive enzyme in the body. Proteolytic enzymes work systemically, outside the confines of the digestive system, and interact specifically with fibrin to support healthy levels of accumulation. NSK-SD® , is a patented, branded, uniquely produced, and extensively studied enzyme. NSK-SD® is isolated from natto, a food made from fermented soybeans.


    This enzyme has demonstrated, quite consistently, its ability to positively impact cardiovascular health. Clinical research showing the physiological and biochemical benefits of NSK-SD® highlighted in over 30+ published studies in the areas of supporting healthy blood pressure, providing critical fibrinolytic activity and supporting healthy levels of platelet and red blood cell aggregation as well as optimal blood viscosity.2,3


    Bergamot


    Citrus bergamia, known as Bergamot, a fragrant fruit the size of an orange with a yellow color similar to a lemon is included in this formulation. It’s been clinically shown to support heart health by promoting healthy cholesterol, blood sugar, and triglyceride levels and supporting blood vessel function.3 


    CurcuPrime® (Tetrahydrocurcumin)


    CurcuPrime® Curcumin is an essential piece of the metabolic and cardiovascular puzzle. While there are often variations in the active percentage of curcumin, Cardio Prime+ features Tetrahydrocurcumin (4HC). This is a partially reduced derivative of curcumin so it is NOT found in turmeric. However, it is one of, if not the, most potent metabolite of curcumin. 4HC is also known for being more stable than curcumin because it has superior absorption and bioavailability properties. Tetrahydrocurcumin is well known for its anti-oxidative and cytoprotective activities. Its ability to reach target tissue and be stored for later use has also been a mechanism that has been identified. In fact, it was found that even without the presence of curcumin, tetrahydrocurcumin is stored in adipose tissue for four weeks after ingestion.4


    Tetrahydrocurcumin has many more desirable biological and pharmacological properties than curcumin. Beyond the fact that 4HC has demonstrated a prolonged plasma half-life when compared to standard curcumin, it has been recognized as a potent antioxidant that supports a series of metabolic and overall health benefits including supporting healthy blood sugar and insulin levels, healthy HDL and triglyceride levels, supporting the structure and function of hepatic cells and supporting healthy blood pressure levels.4


    VasoDrive-AP®


    VasoDrive-AP® - Rounding out this formulation and staying true to our amino acid roots, we’ve included a triamino in Cardio Prime+. The role of aminos in cardiometabolic health is well documented and VasoDrive-AP®, derived from casein (milk protein), and consisting of two aminos - Valine-Proline-Proline (VPP) and Isoleucine-Proline-Proline (IPP) (both of which have been shown to help optimize blood vessel constriction, which in turn, aids with blood flow) represents one of the most innovative aminos available..

  • REFERENCES

    1. Sumi H, Hamada H, Nakanishi K, et al. Acta Haematol 1990;84:139-43. DOI: 10.1159/000205051Sumi

    2. Ross Walker, Elzbieta Janda and Vincenzo Mollace. Cardiac Health and Polyphenols. Chp 84, Pg 1085-1103, 2014. http://dx.doi.org/10.1016/B978-0-12-398456-2.00084-0

    3. Micaela Gliozzi, Ross Walker, Elzbjeta Janda, Vincenzo Mollace. International Journal of Cardiology Dec 2013, 170(2):140-5. https://doi.org/10.1016/j.ijcard.2013.08.125

    4. ZX, Su ZR. Curcumin's Metabolites, Front Pharmacol. 2018 Oct 17;9:1181. https://doi:10.3389/fphar.2018.01181.

Nutrition
Serving Size: 2 capsules | 30 servings per container
IngredientsAmount Per Serving
Niacin (as Cuprous Niacin)
0.83 mg
Copper (as Cuprous Niacin)
0.2 mg
NAD3™ Proprietary Blend
    Wasabi extract (Wasabia japonica)
    Theacrine
     Cuprous Niacin
312 mg
VasoDrive AP® [Isoleucy/-prolyl-proline (IPP) and Valyl-prolyl-proline (VPP)
508 mg
Citrus Bergamot Extract (Fruit)
250 mg
CurcuPrime® Tetrahydrocurcumin
200 mg
NSK-SD Nattokinase (2,000 FU)(soy)
100 mg

Other Ingredients: Microcrystalline Cellulose, Magnesium Stearate (Vegetable), Silica, Vegetable Capsule (Hypromellose). Contains soy and milk.

Your Peers Approve. See Why

4.9
Rated 4.9 out of 5 stars
Based on 752 reviews
Total 5 star reviews: 704 Total 4 star reviews: 46 Total 3 star reviews: 2 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend these products
Reviews Summary
Customers say these supplements are effective and work as described. They appreciate the website's easy navigation, clear product descriptions, and streamlined ordering process. Users report fast shipping and reliable delivery, with many praising the professional packaging. The subscription service receives positive feedback for transparency, with customers liking the advance notifications before auto-renewals. Many reviews mention responsive customer service and quick resolution of issues. While some note the products are not the cheapest option, customers feel they receive good value for the quality provided. Several users report positive experiences with specific products for recovery and energy.
752 reviews
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Practitioners Recommend

Cardio Prime+ Heart Health Supplement: FAQs

Looking for ways to support cardiovascular wellness beyond diet and exercise?

InfiniWell’s Cardio Prime+ supports healthy circulation, blood vessel flexibility, and overall cardiometabolic wellness with compounds like lactotripeptides, citrus bergamot extract, and nattokinase. When combined with a diet rich in whole grains, fruits, vegetables, and other plant foods—as well as regular physical activity and other healthy habits—Cardio Prime+ helps reinforce overall cardiovascular wellness.

Adults who want to take a proactive approach to heart and metabolic wellness will find Cardio Prime+ a good fit.

Have more questions? We have answers

InfiniCare—your personal concierge for longevity. Our team of experts, including our on-staff physician, are standing by to ensure world-class service.

Go to Live Chat Call Us 1-888-819-4640

Our team is located in Dallas, TX, USA

  • What are heart health supplements, and why might I consider them?

    Heart health supplements are dietary products designed to support cardiovascular wellness. They’re meant to be used alongside a healthy diet and lifestyle and often include vitamins, minerals, amino acids, and plant extracts that help maintain blood vessel function and overall cardiovascular balance.

    While whole foods, fruits, vegetables, and physical activity remain the foundation of cardiovascular wellness, supplements like Cardio Prime+ can provide targeted nutrients that may not be easy to get consistently from diet alone.

  • What is Cardio Prime+ by InfiniWell?

    Cardio Prime+ is a dietary supplement created to support overall cardiovascular wellness. Its multi-ingredient formula promotes:

    • Healthy blood flow and vessel flexibility
    • Support for cardiovascular balance as part of a healthy lifestyle
    • Support for the body’s natural processes for healthy circulation
    • Overall cardiometabolic wellness
    If you’re looking for a well-rounded supplement for heart wellness, Cardio Prime+ is worth considering as part of a broader wellness approach.

  • How does Cardio Prime+ work?

    Cardio Prime+ combines nutrients and bioactive compounds that support different aspects of cardiovascular function:

    • Niacin and copper: Support normal enzyme function and energy production
    • NAD3® proprietary blend: A combination of wasabi extract, theacrine, and cuprous niacin that promotes cellular energy production and supports vascular function
    • Lactotripeptides (VasoDrive AP®): Small protein fragments that emerging research suggests may support cardiovascular wellness
    • Citrus bergamot extract: Supports overall cardiometabolic wellness as part of a balanced lifestyle
    • CurcuPrime® tetrahydrocurcumin: Serves as an antioxidant, supporting the body’s natural wellness processes
    • NSK-SD® nattokinase: A naturally derived enzyme that supports the body’s natural processes involved in healthy circulation
    Together, these compounds promote blood vessel flexibility, healthy circulation, and overall cardiometabolic balance.

  • What makes Cardio Prime+ different from other supplements for heart wellness?

    Supplements can vary widely in quality and formulation. Cardio Prime+ uses scientifically researched ingredients that go beyond basic vitamins and minerals, supporting multiple aspects of cardiovascular function, such as vessel flexibility, cardiometabolic balance, and circulation.

    Cardio Prime+ complements more common supplements such as fish oil or vitamin E by including unique compounds not typically found in those products, like nattokinase and lactotripeptides, offering a broad approach to cardiovascular support.

  • Who should consider taking a cardio supplement like Cardio Prime+?

    Cardio Prime+ is formulated for adults who want to:

    • Support healthy circulation and cardiovascular wellness
    • Promote vascular flexibility
    • Support overall cardiometabolic wellness
    • Take a proactive, long-term approach to heart wellness
    Always consult a qualified healthcare professional before adding new supplements, especially if you’re currently taking any medications or working with a healthcare professional.

  • How do I take Cardio Prime+?

    Take two capsules with water each day, or follow the guidance of a qualified healthcare professional. Daily use is recommended, with each serving consisting of two capsules.

  • What are the benefits of Cardio Prime+?

    Cardio Prime+ provides broad cardiovascular support through carefully selected, scientifically researched ingredients. Benefits can include:

    • Vessel flexibility: Ingredients like lactotripeptides and citrus bergamot extract help support normal blood vessel flexibility, which plays a key role in how efficiently your body moves blood throughout the day.
    • Cardiovascular balance: Cardio Prime+ is a multi-ingredient formula that works across several aspects of heart wellness at once, rather than targeting just one area. It takes a broad-spectrum approach to everyday cardiovascular support.
    • Healthy circulation: Nattokinase, a naturally derived enzyme, supports the body's natural processes involved in healthy circulation, an important factor in staying energized and feeling your best.
    • Cardiometabolic wellness: Heart function and metabolic function are closely connected. Cardio Prime+ includes compounds that support both systems together, helping you take a more complete approach to long-term wellness.

  • Is Cardio Prime+ safe for daily use?

    Yes. Cardio Prime+ is designed for regular use with ingredients generally recognized as safe when taken as directed. Before adding any new supplement to your routine, consider speaking with a qualified healthcare professional.

  • How do I support my heart wellness naturally?

    A heart-healthy lifestyle starts with whole foods like fruits, vegetables, whole grains, and plant foods. Guidelines from leading health organizations recommend: 

    • Limiting added sugar
    • Getting regular physical activity
    • Including sources of healthy fatty acids in your diet, such as fish or nuts
    Supplements like Cardio Prime+ can provide additional support when combined with these habits.

  • Do I need supplements if I already follow a healthy diet?

    A balanced diet is the foundation of good heart wellness, but supplements can help fill gaps and provide added support. Even with healthy eating, some nutrients are difficult to get in consistent amounts every day. For instance, a fiber supplement can be useful if your intake from fruits, vegetables, or whole grains is low.

    Emerging research suggests that compounds like lactotripeptides and citrus bergamot extract may also support cardiovascular wellness, making supplements a helpful complement to diet and lifestyle rather than a replacement.

  • Can heart wellness supplements support overall cardiovascular balance?

    Early research suggests citrus bergamot extract may help support overall cardiovascular balance, while omega-3 fatty acids mainly support heart wellness and overall cardiovascular function.

    Supplements aren’t a replacement for a balanced diet or lifestyle, but they can help support overall cardiovascular wellness when used as part of a broader plan.

  • Disclaimer

    This content is for general informational purposes only and is not medical advice. Always talk to a qualified healthcare professional before starting any new supplement or making changes to your wellness routine. 

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.