DHH-B MAX
Mood Support*
- Promotes an Overall Sense of Calm
- Helps Promote Relaxation & Reduced Nervousness
- Maintains Healthy Neurotransmitter Release (Specifically, GABA)
- Promotes Both Healthy REM & Non-REM Sleep Cycles
Active Ingredient: DHH-B (Dihydrohonokiol-B)
Other Ingredients: Cellulose, Rice Powder, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose, Titanium Dioxide)
Take 1 capsule as needed or as directed by your healthcare practitioner.
As needed
1 Capsule
SHOULD NOT BE TAKEN WITH ALCOHOL.
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Benefits
- Promotes an Overall Sense of Calm
- Helps Promote Relaxation & Reduced Nervousness
- Maintains Healthy Neurotransmitter Release (Specifically, GABA)
- Promotes Both Healthy REM & Non-REM Sleep Cycles
-
Ingredients
Active Ingredient: DHH-B (Dihydrohonokiol-B)
Other Ingredients: Cellulose, Rice Powder, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose, Titanium Dioxide)
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How To Use
HOW
Take 1 capsule as needed or as directed by your healthcare practitioner.
WHEN
As needed
DOSE
1 Capsule
NOTES
SHOULD NOT BE TAKEN WITH ALCOHOL.
DHH-B MAX
Mood Support*
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OVERVIEW
OVERVIEW
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IMPACT ON GABA AND OTHER NEUROTRANSMITTERS
DHH-B exerts its biological effects through multiple mechanisms, contributing to its diverse pharmacological activities. One of its primary mechanisms of action is through GABAergic modulation. It acts as a positive allosteric modulator of gamma-aminobutyric acid (GABA) receptors, enhancing GABAergic neurotransmission.
In addition to its GABAergic effects, DHH-B also influences the release and reuptake of various other neurotransmitters, including dopamine, serotonin, and norepinephrine. By promoting levels of these neurotransmitters, DHH-B exhibits potential support for mood, relaxation, and coganative function. -
ANTIOXIDANT SUPPORT
Another important aspect of DHH-B is its ability to support the production of cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukins (IL-1β, IL-6).
Furthermore, DHH-B displays robust antioxidant properties. It is a scavenger of reactive oxygen species (ROS) and upregulates endogenous antioxidant enzymes. These antioxidant effects contribute to its neuroprotective and anti-aging properties. DHH-B’s antioxidant and neuroprotective properties make it a candidate for supporting neurologic physiology and functionality to promote both short term and long term brain health. -
REFERENCES
1. Lin Y, Li Y, Zeng Y, Tian B, Qu X, Yuan Q, Song Y. Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update. Front Pharmacol. 2021 Mar 17;12:632767. doi: 10.3389/fphar.2021.632767. PMID: 33815113; PMCID: PMC8010308.
2. Shen JL, Man KM, Huang PH, Chen WC, Chen DC, Cheng YW, Liu PL, Chou MC, Chen YH. Honokiol and magnolol as multifunctional antioxidative molecules for dermatologic disorders. Molecules. 2010 Sep 16;15(9):6452-65. doi: 10.3390/molecules15096452. PMID: 20877235; PMCID: PMC6257695.
3. Hou Y, Aboukhatwa MA, Lei DL, Manaye K, Khan I, Luo Y. Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice. Neuropharmacology. 2010 May;58(6):911-20. doi: 10.1016/j.neuropharm.2009.11.002. Epub 2009 Nov 14. PMID: 19917299; PMCID: PMC2838959.
4. Woo SM, Seo SU, Kubatka P, Min KJ, Kwon TK. Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation. Biomolecules. 2019 Dec 6;9(12):838. doi: 10.3390/biom9120838. PMID: 31817770; PMCID: PMC6995549.
5. Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP. Honokiol: a novel natural agent for cancer prevention and therapy. Curr Mol Med. 2012 Dec;12(10):1244-52. doi: 10.2174/156652412803833508. PMID: 22834827; PMCID: PMC3663139.

Ingredients | Amount Per Serving |
DHH-B (dihydrohonokiol-B) (derived from magnolia bark) | 15 mg |
Other Ingredients: Cellulose, Rice Powder, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule (Hypromellose, Titanium Dioxide)
Professional Information
People Requiring:
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Stress & Sleep Protocols
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Mood & Neurological Protocols
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Inflammation Support
FAQs
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What is DHH-B Max?
DHH-B Max by InfiniWell is a dietary supplement that contains dihydrohonokiol-B, a bioactive compound extracted from magnolia bark. Research suggests DHH-B has potential calming effects and can help modulate GABA, a neurotransmitter involved in stress regulation, relaxation, and sleep quality.Unlike traditional sedatives, DHH-B doesn’t cause grogginess or dependence, making it a natural alternative for those seeking to support cognitive function, emotional well-being, and even exercise performance through improved rest and mental clarity.
DHH-B’s antioxidant properties may help protect against oxidative stress and support cellular resilience. When combined with different antioxidants—such as vitamin C, beta carotene, or vitamin E—it may offer complementary support for both brain and body. -
What results can I expect from taking DHH-B Max?
DHH-B Max helps promote a sense of calm, both mentally and physically, by supporting neurotransmitter balance and providing antioxidant support.Key DHH-B benefits may include:- Reduced nervous tension: Supports a calmer mood by promoting GABA activity, helping regulate the brain’s response to stress.
- Relaxation without sedation: Ideal for daytime use or when you need to wind down without impairing alertness.
- Better sleep cycles: Supports both REM and non-REM phases of sleep, helping you stay asleep longer and wake up feeling refreshed.
- Mood support: Helps regulate emotions and may promote a more balanced outlook during times of stress.
- Antioxidant properties: May help protect the brain from free radical damage linked to stress and aging.
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How does DHH-B support mood and brain health?
DHH-B Max supports GABA activity. GABA is a naturally occurring neurotransmitter that helps calm overactive neural pathways. A drop in GABA levels is often linked to heightened stress, restlessness, or racing thoughts.By promoting healthy GABA signaling, DHH-B promotes:- A more relaxed mood
- Less tension during stressful situations
- More consistent, restful sleep
- Sharper cognitive focus through a calmer mental state
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Is DHH-B an antioxidant supplement?
Yes. DHH-B also exhibits purported antioxidant properties, which may support brain health by helping the body manage oxidative stress, an imbalance that can affect mood, memory, and cellular function.Antioxidant support is especially important for protecting the body’s cells from reactive oxygen species (ROS), unstable molecules that can build up from poor sleep, chronic stress, or strenuous activity.
DHH-B Max may be taken alongside other antioxidant supplements, such as vitamin C and vitamin E, to support overall wellness. -
How should I take DHH-B Max?
Take 1 capsule as needed or as directed by your healthcare provider. DHH-B Max is typically taken:- In the evening to support healthy sleep cycles
- During the daytime to manage acute stress or nervous tension
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How quickly does DHH-B Max work?
Many users report a calming effect within 30 to 60 minutes of taking DHH-B Max. With regular use, it may also support longer-term benefits like better sleep, improved mood, and a more balanced response to stress. -
Who should take InfiniWell DHH-B Max?
DHH-B Max may support a wide range of individuals looking for mood and sleep support:- Professionals managing stress or irregular sleep
- Athletes aiming to support post-exertion recovery through improved rest
- Adults seeking non-sedative support for nervous tension
- Individuals looking to support relaxation and sleep quality through targeted daily supplementation
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Is DHH-B Max habit-forming?
No. Unlike traditional sleep aids or anti-anxiety medications, DHH-B isn’t a sedative and doesn’t carry a risk of dependency. Instead of shutting down brain activity, it supports your body’s natural pathways for calm and relaxation. -
What distinguishes InfiniWell DHH-B Max from similar formulations on the market?
InfiniWell DHH-B Max uses high-purity dihydrohonokiol-B and is carefully formulated without unnecessary fillers. The formula is backed by clinical insights and designed for targeted mood and sleep support.Key differentiators include:- Single active ingredient: You know exactly what you’re getting. No proprietary blends or hidden ingredients.
- Stimulant-free and non-drowsy: It helps you stay calm without slowing you down.
- Third-party tested: Every batch is produced in a GMP-certified facility for quality and consistency.
- Doctor-formulated: The formula is designed with scientific rigor to support mental clarity, sleep, and mood balance.
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Can I stack DHH-B Max with other supplements?
Yes. DHH-B Max can be safely combined with other dietary supplements, especially those supporting sleep, cognitive function, or antioxidant activity:- Vitamins C and E for antioxidant support
- Adaptogens like ashwagandha for stress regulation
- Melatonin or magnesium for occasional sleep support
- Omega-3s for brain and mood health
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How can I naturally increase my body's antioxidants?
One of the most effective ways to support your body’s natural antioxidant defenses is by increasing your fruit and vegetable intake. These foods are rich in beneficial plant chemicals—such as flavonoids, carotenoids, and polyphenols.Eating various antioxidant-rich foods like berries, leafy greens, tomatoes, carrots, and citrus fruits can help neutralize free radicals and promote long-term health. Consistent vegetable intake, in particular, has been linked to stronger cellular defense, healthy brain function, and a lower risk of oxidative stress–related concerns.
Incorporating more whole, colorful plant foods into your daily meals is a simple and powerful step toward strengthening your body’s defenses. -
Is there anything I should be aware of when taking antioxidant supplements?
Yes. While antioxidant supplements—such as vitamin E supplements and other dietary antioxidant vitamins—can support overall wellness, it’s important to be mindful of amounts, timing, and individual health needs. Research suggests that high-dose supplementation may not offer additional benefits and, in some cases, could interfere with medications or nutrient absorption, especially when combined with certain mineral supplements.Some studies have evaluated the use of antioxidant supplements for secondary prevention (preventing further health issues in those already at risk), but overall, the evidence does not support consistent benefits in this context. However, outcomes may vary based on baseline characteristics such as age, existing health conditions, and overall nutritional status. For example, antioxidant use may affect how the body responds to blood pressure regulation or interact with other nutrients, particularly when taken in high doses or combined with other supplements.
It’s also worth noting that combining multiple antioxidants into a single antioxidant cocktail doesn't always lead to better outcomes. Instead of focusing on taking supplements alone, aim to support your health with a balanced diet rich in plant-based antioxidants, and consult your healthcare provider before starting a new supplement routine, especially if you’re managing a condition or taking other medications. -
Glossary
Key terms to know:- Antioxidant activity: The ability to neutralize reactive oxygen species (ROS), which can damage cells and impair cognitive or physical performance.
- Antioxidant enzymes: Proteins produced by the body that help neutralize free radicals and minimize oxidative damage. They work alongside dietary antioxidants to support the body’s internal defense system.
- Antioxidant supplements: Nutrients such as vitamin C, beta carotene, and vitamin E that support cellular protection and brain function. Antioxidant supplementation may help reduce oxidative stress, support immune health, and promote overall wellness, especially when dietary intake of antioxidants is limited.
- Antioxidant therapy: A structured approach that uses antioxidants—through diet, supplements, or clinical protocols—to support the body’s defense against oxidative stress. Antioxidant therapy is studied in research and integrative health for its role in supporting brain function, long-term health, and healthy aging.
- Antioxidant support strategies: A general term for the use of antioxidants to support wellness or target specific health concerns. Antioxidant strategies may involve supplements like vitamin C, vitamin E, or beta carotene, along with antioxidant-rich foods, to support secondary prevention and cellular protection.
- Beta carotene supplementation: The practice of taking beta carotene supplements. Beta carotene is a plant-based antioxidant that the body converts into vitamin A and has been studied for its role in supporting eye, immune, and skin health. However, high amounts may pose risks, especially for smokers. When used appropriately, beta carotene supports overall wellness, like other antioxidants.
- Clinical trial: A research study conducted with human participants to evaluate the safety, effectiveness, or potential health benefits of a medical intervention, such as a supplement, drug, or procedure. Clinical trials follow a structured design and are often conducted in phases to assess outcomes over time.
- DHH-B (dihydrohonokiol-B): A compound found in magnolia bark, known for its calming and antioxidant effects without sedation.
- Dietary antioxidants: Compounds found in foods that help protect the body’s cells from damage caused by free radicals. These include naturally occurring antioxidants like vitamin C, vitamin E, and beta carotene.
- GABA (gamma-aminobutyric acid): A neurotransmitter that inhibits stress signals in the brain, promoting relaxation and sleep.
- GABA signaling: The process by which GABA communicates with receptors in the brain to regulate neural activity, supporting calm, relaxation, and healthy sleep patterns.
- Integrative health: A holistic approach that combines conventional medicine with complementary practices, including natural supplements like DHH-B.
- Post-exertion muscle recovery: The process of rebuilding and repairing muscle tissue after exercise, often supported by restful sleep and antioxidant intake.
- Oxidative stress: An imbalance between free radicals and antioxidants in the body. DHH-B may support the body's antioxidant defense.
- Randomized trials: A type of clinical study where participants are randomly assigned to receive either the treatment being tested or a control (such as a placebo). Randomized trials are considered the gold standard in research because they minimize bias and help determine whether a treatment has a significant benefit over no treatment or another intervention.
- REM and non-REM sleep: The two main types of sleep that help the body and brain recover. REM (rapid eye movement) sleep is linked to dreaming and cognitive function, while non-REM supports physical restoration. DHH-B may support the full sleep cycle for better rest.
- Systematic review: A type of research summary that collects and critically analyzes multiple studies on a particular topic, following a standardized, transparent process. Systematic reviews aim to provide a comprehensive and unbiased overview of available evidence to guide healthcare decisions.