EPICATECHIN
Cardiovascular Support & Muscle Function*
- Strength Gains
- Stamina & Endurance
- Nitric Oxide Support
- Antioxidant & Metabolic Support
- Muscle Protein Synthesis & Muscle Recovery
Active Ingredient: Epicatechin
Other Ingredients: Vegetable Capsule (Hypromellose, Titanium Dioxide)
HOW
Take 2 capsules daily with water or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
2 Capsules
-
Benefits
- Strength Gains
- Stamina & Endurance
- Nitric Oxide Support
- Antioxidant & Metabolic Support
- Muscle Protein Synthesis & Muscle Recovery
-
Ingredients
Active Ingredient: Epicatechin
Other Ingredients: Vegetable Capsule (Hypromellose, Titanium Dioxide)
-
How To Use
HOW
Take 2 capsules daily with water or as directed by your healthcare practitioner.
WHEN
Daily
DOSE
2 Capsules
EPICATECHIN
Formulation
Epicatechin
- Found In
- Green Tea, Cacao
- Source
- 2,3-cis-epicatechin
- Benefits
- Muscle Building, Heart, Brain Health
- Science
- 18,814 published articles
Cardiovascular Support & Muscle Function*
-
OVERVIEW
Epicatechin is a flavanol compound naturally present in cocoa, green tea, and berries. It has been researched for its antioxidant properties and its potential to support various physiological functions. Epicatechin helps neutralize free radicals, which are known to cause oxidative stress, and supports cellular health. It has been shown to influence nitric oxide production, which plays a role in promoting healthy blood flow. Studies suggest that epicatechin may also support glucose metabolism and muscle physiology through mechanisms such as myostatin modulation and protein synthesis enhancement, areas that require further clinical investigation for confirmation of its effects.
-
MUSCLE GROWTH, PERFORMANCE, & RECOVERY
Research has indicated that epicatechin may interact with pathways related to muscle physiology. Myostatin is a protein involved in regulating muscle growth, and some studies suggest that epicatechin may influence myostatin signaling, a pathway associated with muscle development and adaptation.1
Epicatechin is also involved in supporting protein synthesis, which is critical for muscle repair and maintenance. Preliminary research has indicated a potential benefit for those engaging in resistance training or exercise by supporting muscle adaptation and recovery.2 Additionally, epicatechin has been observed to influence skeletal muscle contractility and energy production by interacting with cellular pathways such as calcium release and mitochondrial biogenesis.3 -
NITRIC OXIDE PRODUCTION
Epicatechin has been studied for its role in supporting the body’s production of nitric oxide (NO) through its interaction with endothelial nitric oxide synthase (eNOS). NO is involved in vascular function, contributing to the relaxation of blood vessels and promoting healthy blood flow. Research suggests that this mechanism may support cardiovascular and cognitive function.4
-
ANTIOXIDANT ACTIVITY
Epicatechin demonstrates antioxidant activity through multiple mechanisms. It directly neutralizes reactive oxygen species (ROS) and reactive nitrogen species (RNS), reducing oxidative stress in the body. Additionally, it may enhance the activity of endogenous antioxidant enzymes such as superoxide dismutase (SOD) and catalase, which further supports the body’s defense against oxidative damage.5
-
REFERENCES
1. Walker DK, Dickinson JM, Timmerman KL, et al. Exercise, amino acids, and aging in the control of human muscle protein synthesis. Med Sci Sports Exerc. 2011;43(12):2249-2258. doi: 10.1249/MSS.0b013e318223b037
2. Gutierrez-Salmean G, Ciaraldi TP , Nogueira L, et al. Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. J Nutr Biochem. 2014;25(1):91-94. doi: 10.1016/j.jnutbio.2013.09.010
3. Gutiérrez-Salmeán G, Ortiz-Vilchis P , V acaseydel CM, Rubio-Gayosso I, Meaney E, Villarreal F, Ramírez-Sánchez I, Ceballos G. Acute effects of an oral supplement of (-)-epicatechin on postprandial fat and carbohydrate metabolism in normal and overweight subjects. Food Funct. 2014 Mar;5(3):521-7. doi: 10.1039/c3fo60416k. PMID: 24458104; PMCID: PMC3947792.
4. Rassaf T, Rammos C, Hendgen-Cotta UB, et al. V asculoprotective effects of dietary cocoa flavanols in patients on hemodialysis: a double-blind, randomized, placebo-controlled trial. Clin J Am Soc Nephrol. 2016;11(1): 108-118. doi: 10.2215/CJN.04030415
5. Higginbotham S, Zhang ZF, Lee IM, et al. Dietary flavonoids and the risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2005;14(4): 913-918. doi: 10.1158/1055-9965.EPI-04-0688
| Ingredients | Amount Per Serving |
| Epicatechin | 500 mg |
Other Ingredients: Vegetable Capsule (Hypromellose, Titanium Dioxide)
Professional Information
People Requiring:
-
Workout Endurance & Stamina Support
-
Muscle Recovery Support
-
Exercise-Related Muscle Soreness Aid
-
Lean Muscle Mass Maintenance Support
Your Peers Approve See Why
- Peter N.Verified Buyer2 days agoReviewingEPICATECHINRated 3 out of 5 starsOk so far
I will say since I started taking this product my workouts are much better and that my muscles feel better the next day after a intense workout.
Infiniwell2 hours agoThank you so much for sharing your experience, Peter! We're thrilled to hear that Strength is helping enhance your workouts and supporting your recovery. If you have any questions or need support along the way, feel free to reach out to our InfiniCare team.
- Nilo G.Verified Buyer1 month agoReviewingEPICATECHINRated 5 out of 5 starsRepeat buyer
Although not with very obvious signs, there has been a clear difference when I’m on Epicathechin and when I’m not. The muscle gains are definitely noticeable for the user that keeps track of it. If you’re doing the right work and diet, this product has given me an edge in terms of acquiring slightly more lean muscle mass. I don’t take it continuously, I’m off for weeks then resume it for weeks. I definitely see the benefits and difference.
- Sandra B.Verified Buyer2 months agoReviewingEPICATECHINRated 5 out of 5 starsStronger muscles, flatter tummy
My measured exercise performance has improved and my tummy is flatter (loss of visceral fat) in the 6 weeks I’ve been taking epicatechin. Yay
- Jason R.Verified Buyer3 months agoReviewingEPICATECHINRated 4 out of 5 starsSeems to work well
Great product
- Emily P.Verified Buyer3 months agoReviewingEPICATECHINRated 5 out of 5 starsEpicatechin is an under appreciated compound.
I’ve taken InfiniWell’s Epicatechin for upwards 5 years. It’s an under appreciated compound IMHO, as it truly supports my efforts at maintaining my hard earned muscle at 49 years young. When I take breaks, I soften a bit. I’ve tried other brands, but Infiniwell is noticeably more effective.
Practitioners Recommend
BPC-157 RAPID PRO - 500MCG
Muscle, Joint & Gut Support*
BPC-157 Probiotic | ABC
Peptide | Live Probiotic*
STRENGTH
Support For Muscle Mass & Tissue Quality*
CONTROL
Glucose Metabolism & Insulin Sensitivity*
OMEGA 5x
Unlock the Therapeutic Potential of Omega-3*
FAQs
-
What is epicatechin?
Epicatechin is a bioactive compound found in dark chocolate, green tea, and certain fruits like apples, grapes, and berries. It’s been studied in both human and animal models for its beneficial effects on oxidative capacity, blood flow, and skeletal muscle adaptation.Research has shown that epicatechin supplementation may:- Support nitric oxide production
- Maintains a healthy balance of myostatin and follistatin (muscle growth regulators)
- Promote mitochondrial biogenesis (the process of creating new mitochondria to support energy production)
- Encourage muscle protein synthesis (the process of building new muscle proteins for growth and repair)
-
What are the benefits of taking an epicatechin supplement?
InfiniWell Epicatechin is formulated to support various fitness and wellness goals. Some of the most cited effects of epicatechin include:Strength gains and muscle size
Epicatechin helps balance myostatin gene expression, the process by which the body produces myostatin, a protein that limits muscle growth. This may support muscle mass maintenance and development—especially when combined with resistance training.
Endurance and recovery
This supplement supports oxygen uptake, nutrient delivery, and muscle recovery during strenuous exercise by encouraging better blood flow and cellular energy production, helping you bounce back faster between training sessions.
Blood flow and vascularity
Epicatechin promotes healthy circulation and vascularity through nitric oxide pathways (the body's natural process for relaxing blood vessels). This may contribute to improved muscle pump, sustained energy, and overall cardiovascular support during physical activity.
Antioxidant defense
It helps combat exercise-induced oxidative stress by neutralizing free radicals and supporting the body’s natural antioxidant systems, which may protect cells and tissues during intense workouts.
Metabolic support
Epicatechin may help aid insulin sensitivity (how effectively the body responds to insulin) and support efficient energy metabolism, which is important for maintaining stable blood sugar levels, fueling workouts, and supporting body composition goals. -
How does epicatechin support muscle growth?
Epicatechin influences key pathways involved in skeletal muscle development. Specifically, it has been shown to:- Suppress myostatin levels (including relative myostatin mRNA expression)
- Support muscle protein synthesis
- Promote increases in skeletal muscle mass and strength when combined with consistent training
- Encourage aerobic training adaptations through improved oxygen uptake
- Potentially increase mitochondrial biogenesis, helping the body meet energy demands during prolonged activity
-
What’s the recommended amount for epicatechin supplements?
For optimal absorption, the suggested serving size is 2 capsules daily with water on an empty stomach. It's best taken in the morning or before workouts. Each serving provides a total of 500 mg of isolated epicatechin.As with any supplement, it's important to consult your healthcare provider before starting a new regimen. -
How long does it take for epicatechin to work?
Some individuals report noticing changes such as improved muscle blood flow, better training sessions, or quicker post-workout recovery within 1–2 weeks.More noticeable support for performance-related goals—such as workout stamina or power output—may take 4–8 weeks of consistent resistance or endurance training, along with nutrition and supplementation practices. -
Who should take InfiniWell Epicatechin?
This supplement is ideal for individuals looking to support skeletal muscle adaptation, maintain cardiovascular health, or promote endurance as part of an active lifestyle:- Fitness enthusiasts, athletes, and strength trainers
- Those focused on maintaining muscle function in the context of age-related or genetic muscle concerns (with guidance)
- Anyone looking to support exercise performance or maintain cardiovascular function
-
Is epicatechin a steroid?
No. Epicatechin is a naturally occurring plant compound—not a steroid or synthetic hormone. Its mechanism of action involves gene expression modulation (e.g., myostatin expression) and vascular support through nitric oxide pathways. -
Is epicatechin safe?
Yes, epicatechin supplements are generally well-tolerated when taken as directed. InfiniWell’s formula is:- Physician-formulated
- Third-party tested
- Free from banned or stimulant ingredients
-
What is nitric oxide, and why does it matter?
Nitric oxide (NO) is crucial for blood vessel dilation, which supports nutrient delivery, oxygen uptake, and muscle blood flow. By helping the body increase nitric oxide production, epicatechin promotes:- Exercise endurance capacity
- Heart health
- Improved vascular function and aerobic performance
-
What makes InfiniWell’s epicatechin supplement different?
InfiniWell Epicatechin stands out for its quality, transparency, and research-aligned formulation:Clinical-strength dosage
Each capsule contains 250 mg of epicatechin, matching the daily intake levels commonly used in human studies on muscle health, vascular function, and antioxidant support.
Clean, stimulant-free formula
The product is free from artificial fillers, proprietary blends, and unnecessary additives, so you know exactly what you’re getting.
Produced to high standards
This supplement is made in a Good Manufacturing Practice (GMP)-certified facility to ensure consistency, purity, and potency in every batch.
Designed for active performance
It is intended to support muscle size, blood flow, and endurance, especially when paired with regular training and a balanced lifestyle. -
Can I stack epicatechin with other supplements?
Yes. Epicatechin can be taken alongside other nutritional supplements, such as protein powders, creatine, or nitric oxide boosters, to support your overall training goals:- Protein powders to support muscle building
- Creatine for strength and power output
- Supplements that support nitric oxide production (like beetroot or citrulline) for healthy blood flow and muscle pump
- Post-workout recovery formulas to help with muscle repair and fatigue
When used as part of a structured routine, stacking may complement other supplements aimed at supporting myostatin activity, anaerobic performance, or muscle recovery.
Before beginning any supplement regimen—or combining different products—it's best to talk with your healthcare provider, particularly if you’re managing a health condition or currently taking medication. -
Terms to know
Glossary of terms:- Epicatechin: A natural flavonoid found in cocoa, green tea, and some fruits, known for its supportive effects on muscle health, vascular function, and antioxidant activity.
- Myostatin: A protein that regulates muscle growth by limiting muscle development. Lower myostatin levels are linked to increased skeletal muscle mass.
- Nitric oxide: A molecule produced by the body to relax and widen blood vessels, improving circulation, oxygen uptake, and nutrient delivery to muscles.
- Gene expression: The biological process through which genetic information is used to produce proteins. Epicatechin may influence gene expression related to muscle growth, such as myostatin.
- Myostatin inhibition: The process of reducing myostatin activity to promote muscle development. This is one of the potential mechanisms linked to epicatechin’s muscle-supportive effects.
- Relative myostatin mRNA expression: A measurement of how actively the body is producing myostatin at the genetic level, often used in research to track changes in muscle growth regulation.
- Relative peak anaerobic power: A measure of short-term, high-intensity power output during anaerobic exercise (e.g., sprint cycling), adjusted for body weight. It’s often used in sports science to evaluate performance capacity.
- Insulin sensitivity: The body’s ability to respond efficiently to insulin. Improved insulin sensitivity supports metabolic health and may influence energy use during exercise.
- Anaerobic training adaptations: Physical improvements—like increased power output and fatigue resistance—that result from short bursts of high-intensity activity, where the body primarily uses energy systems that don’t require oxygen (such as sprinting or weightlifting).
- Placebo-controlled clinical studies: Research trials where one group receives the active compound and another receives an inactive substance (placebo) to compare outcomes.
- Placebo group: The group in a clinical study that receives a placebo instead of the active supplement. This helps measure the true effect of a compound like epicatechin.
- Skeletal muscle growth: The increase in size and strength of voluntary muscles, typically supported by consistent resistance training, adequate nutrition, and, in some cases, supplementation or recovery strategies.